结直肠癌：病理方面。
Colorectal carcinoma: Pathologic aspects.
机构信息
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at University of California, Los Angeles, California, USA.
出版信息
J Gastrointest Oncol. 2012 Sep;3(3):153-73. doi: 10.3978/j.issn.2078-6891.2012.030.
Abstract
Colorectal carcinoma is one of the most common cancers and one of the leading causes of cancer-related death in the United States. Pathologic examination of biopsy, polypectomy and resection specimens is crucial to appropriate patient managemnt, prognosis assessment and family counseling. Molecular testing plays an increasingly important role in the era of personalized medicine. This review article focuses on the histopathology and molecular pathology of colorectal carcinoma and its precursor lesions, with an emphasis on their clinical relevance.
摘要
结直肠癌是美国最常见的癌症之一，也是癌症相关死亡的主要原因之一。对活检、息肉切除术和切除标本进行病理检查对于适当的患者管理、预后评估和家庭咨询至关重要。分子检测在个性化医疗时代发挥着越来越重要的作用。本文重点介绍了结直肠癌及其前体病变的组织病理学和分子病理学，并强调了它们的临床相关性。
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