Ichimiya Yukako, Alluri Krishna, Marcus Charles, Best Simon, Chung Christine H, Subramaniam Rathan M
Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University Baltimore, MD.
Department of Otolaryngology and Head and Neck Surgery, Johns Hopkins University Baltimore, MD.
Am J Nucl Med Mol Imaging. 2015 Jan 15;5(2):154-61. eCollection 2015.
The objective of this study is to establish the utilization trends of CT, MRI, and FDG-PET/CT for evaluation of oropharyngeal squamous cell carcinoma (OPSCC) patients. A total of 173 patients with newly diagnosed stage III or IV OPSCC between 2003 and 2009 were included. Frequency of imaging modality use, divided into four time periods (2003-04, 2005-06, 2007-08 and 2009), was evaluated. For initial staging, percentage of PET/CT use was 64.6%, 87.5%, 94.1% and 96.3%, with an increasing trend (p < 0.001). The CT (p = 0.762) and MRI (p = 0.224) use demonstrated no change in trend. For post-treatment imaging, percentage of PET/CT use was 59.5%, 68.6%, 89.7% and 100%, with an increasing trend (p < 0.001). The CT use demonstrated a decreasing trend (p = 0.004) and MRI showed no trend change (p = 0.231). PET/CT is used with an increasing trend for initial staging and has become a central imaging modality for follow up evaluation after treatment, for advanced OPSCC.
本研究的目的是确定CT、MRI和FDG-PET/CT在评估口咽鳞状细胞癌（OPSCC）患者中的使用趋势。纳入了2003年至2009年间共173例新诊断为III期或IV期OPSCC的患者。评估了分为四个时间段（2003 - 04年、2005 - 06年、2007 - 08年和2009年）的成像模态使用频率。对于初始分期，PET/CT的使用百分比分别为64.6%、87.5%、94.1%和96.3%，呈上升趋势（p < 0.001）。CT（p = 0.762）和MRI（p = 0.224）的使用未显示趋势变化。对于治疗后成像，PET/CT的使用百分比分别为59.5%、68.6%、89.7%和100%，呈上升趋势（p < 0.001）。CT的使用呈下降趋势（p = 0.004），而MRI未显示趋势变化（p = 0.231）。PET/CT在初始分期中的使用呈上升趋势，并且已成为晚期OPSCC治疗后随访评估的核心成像模态。
