Pongprayoon U, Bohlin L, Sandberg F, Wasuwat S
Acta Pharm Nord. 1989;1(1):41-4.
An extract of the plant Ipomoea pes-caprae, used in Thailand as a folk remedy for treating dermatitis caused by jellyfish and Portuguese man-of-war, has been tested for antagonistic activity against histamine, acetylcholine, bradykinin and barium chloride on the isolated guinea-pig ileum. The extract reversibly inhibited the contraction induced by all the spasmogens in a concentration-dependent manner and decreased both the slope and the maximal response of the concentration response curves. It is not likely that the extract specifically interferes at the receptor level. It may be due to the direct action of the extract on the ileal smooth muscle.
一种在泰国被用作民间疗法治疗水母和僧帽水母引起的皮炎的植物——马鞍藤提取物，已在离体豚鼠回肠上进行了针对组胺、乙酰胆碱、缓激肽和氯化钡的拮抗活性测试。该提取物以浓度依赖性方式可逆地抑制所有致痉剂诱导的收缩，并降低浓度-反应曲线的斜率和最大反应。该提取物不太可能在受体水平上产生特异性干扰。这可能是由于提取物对回肠平滑肌的直接作用。
