Turan S C, Shah P C, Pietruszko R
Center of Alcohol Studies, Rutgers University, Piscataway, NJ 08855-0969.
Alcohol. 1989 Nov-Dec;6(6):461-4. doi: 10.1016/0741-8329(89)90052-9.
Monoamine oxidase (EC 1.4.3.4) and aldehyde dehydrogenase (EC 1.2.1.3) activities were compared in the liver mitochondria of male and female rats. Monoamine oxidase activity using benzylamine as a substrate was significantly higher in males as compared with females: 1.45 versus 0.74 mumols/mg mitochondrial protein/hr, respectively. Monoamine oxidase activity using tyramine as a substrate and aldehyde dehydrogenase activity were the same in males and females. Monoamine oxidase-tyramine and aldehyde dehydrogenase activities did not vary with the different phases of the estrous cycle in the female but the activity of monoamine oxidase-benzylamine did; rats in the proestrous phase had the highest activity and those in the estrous phase had the lowest.
比较了雄性和雌性大鼠肝脏线粒体中一元胺氧化酶（EC 1.4.3.4）和醛脱氢酶（EC 1.2.1.3）的活性。以苄胺为底物时，雄性大鼠的一元胺氧化酶活性显著高于雌性：分别为1.45和0.74微摩尔/毫克线粒体蛋白/小时。以酪胺为底物时的一元胺氧化酶活性以及醛脱氢酶活性在雄性和雌性大鼠中相同。一元胺氧化酶-酪胺和醛脱氢酶活性在雌性大鼠的发情周期不同阶段并无变化，但一元胺氧化酶-苄胺的活性有变化；动情前期的大鼠活性最高，发情期的大鼠活性最低。
