用于先天性巨细胞病毒感染诊断的尿液采集方法
Urine Collection Method for the Diagnosis of Congenital Cytomegalovirus Infection.
作者信息
Ross Shannon A, Ahmed Amina, Palmer April L, Michaels Marian G, Sánchez Pablo J, Stewart Audra, Bernstein David I, Feja Kristina, Novak Zdenek, Fowler Karen B, Boppana Suresh B
机构信息
From the *Department of Pediatrics, †Department of Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama; ‡Department of Pediatrics, Carolinas Medical Center, Charlotte, North Carolina; §Department of Pediatrics, University of Mississippi Medical Center, Jackson, Mississippi; ¶Department of Pediatrics, The Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania; ‖Department of Pediatrics, The Ohio State University-Nationwide Children's Hospital, Columbus, Ohio; **Department of Pediatrics, University of Texas Southwestern Medical School, Dallas, Texas; ††Department of Pediatrics, Cincinnati Children's Hospital Medical Center and University of Cincinnati, Cincinnati, Ohio; ‡‡Saint Peter's University Hospital, New Brunswick, New Jersey; and §§Department of Epidemiology, The University of Alabama at Birmingham, Birmingham, Alabama.
出版信息
Pediatr Infect Dis J. 2015 Aug;34(8):903-5. doi: 10.1097/INF.0000000000000757.
Congenital cytomegalovirus infection is traditionally diagnosed by virus detection in saliva or urine. Virus culture was positive in significantly fewer urine samples collected using cotton balls in diapers (55.2%) than with samples collected by bags (93.2%) from newborns screened positive for CMV in saliva. However, polymerase chain reaction was positive in 95% of urine samples regardless of the collection method.
先天性巨细胞病毒感染传统上是通过检测唾液或尿液中的病毒来诊断的。对于唾液中巨细胞病毒筛查呈阳性的新生儿，使用尿布中的棉球采集的尿液样本中病毒培养呈阳性的比例（55.2%）显著低于使用袋子采集的样本（93.2%）。然而，无论采用何种采集方法，聚合酶链反应在95%的尿液样本中呈阳性。
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