Yao S J, Guvench S, Guvench M G, Chan L T, Ruppel-Kerr R, Lien M, Wolfson S K
Department of Neurological Surgery, University of Pittsburgh, Pennsylvania.
ASAIO Trans. 1989 Jul-Sep;35(3):742-4. doi: 10.1097/00002480-198907000-00186.
Thin-film platinum electrodes have been prepared for use in a system for measurement of glucose. Cyclic voltammetry was used to test the electrodes in phosphate and bicarbonate solutions, and in the dialysate of human serum. The peak current output for glucose concentrations between 50-300 mg/dl in a phosphate buffer, and 100-250 mg/dl in the dialysate of human serum, were linear. Two of the three inflection points occurring in the voltammograms are invariant with changes in scan rate, pH, CO2, O2, and glucose. A method for using these points to compensate for voltage drift and current shift is discussed.
已制备出用于葡萄糖测量系统的薄膜铂电极。采用循环伏安法在磷酸盐和碳酸氢盐溶液以及人血清透析液中对电极进行测试。在磷酸盐缓冲液中,葡萄糖浓度在50 - 300mg/dl之间时的峰值电流输出呈线性,在人血清透析液中,葡萄糖浓度在100 - 250mg/dl之间时的峰值电流输出呈线性。伏安图中出现的三个拐点中有两个不受扫描速率、pH值、二氧化碳、氧气和葡萄糖变化的影响。本文讨论了利用这些点来补偿电压漂移和电流偏移的方法。