Daoulah Amin, Ocheltree Sara, Al-Faifi Salem M, Ahmed Waleed, Alsheikh-Ali Alawi A, Asrar Farhan, Lotfi Amir
Section of Adult Cardiology, Cardiovascular Department, King Faisal Specialist Hospital & Research Center, P.O. Box 40047, Jeddah, 21499, Kingdom of Saudi Arabia.
Internal Medicine Department, University of Alabama Huntsville Regional Medical Campus, Huntsville, Alabama, USA.
J Med Case Rep. 2015 May 15;9:113. doi: 10.1186/s13256-015-0596-6.
Sinus arrest, atrio-ventricular block, supraventricular, and ventricular arrhythmias have been reported in patients with sleep apnea syndrome. The arrhythmias usually occur during sleep and contribute to the cardiovascular morbidity and mortality, and the treatment of sleep apnea usually results in the resolution of the brady- arrhythmias. Weight loss, continuous positive airway pressure (CPAP), oral appliances, and upper airway surgery are the recommended treatments, however, compliance and efficacy are issues.
A 58-year-old Arab man presented with recurrent presyncope. He was subsequently diagnosed with sleep apnea associated with frequent and significant sinus pauses. He presented a treatment challenge because he refused continuous positive airway pressure and pacemaker, however, he was successfully treated with theophylline.
Frequent and significant sinus pause associated with sleep apnea was successfully treated with theophylline in our patient when the standard treatment of care was refused.
睡眠呼吸暂停综合征患者中曾有窦性停搏、房室传导阻滞、室上性及室性心律失常的报道。心律失常通常发生在睡眠期间,会导致心血管疾病的发病率和死亡率上升,而治疗睡眠呼吸暂停通常会使缓慢性心律失常得到缓解。减肥、持续气道正压通气(CPAP)、口腔矫治器及上气道手术是推荐的治疗方法,然而,依从性和疗效仍是问题。
一名58岁的阿拉伯男性因反复发生晕厥前症状前来就诊。他随后被诊断为睡眠呼吸暂停伴频繁且显著的窦性停搏。由于他拒绝持续气道正压通气及起搏器治疗,因此带来了治疗挑战,不过,他接受氨茶碱治疗后获得成功。
在我们的患者拒绝标准治疗方案时,氨茶碱成功治疗了与睡眠呼吸暂停相关的频繁且显著的窦性停搏。