皮肤大细胞间变性淋巴瘤
Large cell anaplastic lymphoma of the skin.
作者信息
Feller A C, Sterry W
机构信息
Department of Pathology, University of Kiel, F.R.G.
出版信息
Br J Dermatol. 1989 Nov;121(5):593-602. doi: 10.1111/j.1365-2133.1989.tb08191.x.
Large cell anaplastic lymphoma (LCAL) is a recently described entity recognized by its constant expression of the CD30 antigen and by its morphology. LCAL is classified as high grade malignant lymphoma. We report 10 patients with LCAL of the skin, three with primary LCAL and others in which it developed with cutaneous T-cell lymphoma, mainly mycosis fungoides. The immunophenotype in all but one of these cases, was that of activated T cells.
大细胞间变性淋巴瘤（LCAL）是一种最近才被描述的疾病实体，其通过CD30抗原的持续表达及其形态学特征得以识别。LCAL被归类为高级别恶性淋巴瘤。我们报告了10例皮肤LCAL患者，其中3例为原发性LCAL，其他患者则是在皮肤T细胞淋巴瘤（主要是蕈样肉芽肿）基础上发展而来。除1例患者外，所有这些病例的免疫表型均为活化T细胞。
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