Young Bradley L, Menendez Mariano E, Baker Dustin K, Ponce Brent A
Division of Orthopaedic Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
Division of Orthopaedic Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
J Shoulder Elbow Surg. 2015 Oct;24(10):e271-8. doi: 10.1016/j.jse.2015.04.002. Epub 2015 May 12.
Despite that pulmonary embolism (PE) is a feared complication after shoulder arthroplasty, little is known about its perioperative associated factors.
We used the Nationwide Inpatient Sample to gather a sample of 422,372 patients who underwent shoulder arthroplasty between 2002 and 2011. This population was divided into 2 cohorts on the basis of those who experienced perioperative PE (0.25%) and those who did not. Demographics were compiled for both cohorts. Multivariable logistic regression analysis was used to account for confounding variables and to determine significant predictors of perioperative PE.
After adjusting for patient demographic and clinical variables in multivariable regression modeling, the top 4 independent predictors for PE were primary diagnosis of proximal humerus fracture, deficiency anemia, congestive heart failure, and chronic lung disease. Other pertinent risk factors included increasing age, obesity, fluid and electrolyte abnormalities, undergoing total shoulder arthroplasty rather than hemiarthroplasty, and subsequent days of postoperative care.
Knowledge of these factors might help in preoperative counseling and prove useful for implementation of quality improvement strategies to reduce the occurrence of PE. Surgeons may consider initiating thromboprophylaxis in patients with any of the aforementioned comorbidities.
尽管肺栓塞(PE)是肩关节置换术后令人担忧的并发症,但对其围手术期相关因素知之甚少。
我们使用全国住院患者样本,收集了2002年至2011年间接受肩关节置换术的422372例患者的样本。根据围手术期发生PE的患者(0.25%)和未发生PE的患者,将该人群分为两个队列。对两个队列的人口统计学数据进行了汇总。采用多变量逻辑回归分析来处理混杂变量,并确定围手术期PE的显著预测因素。
在多变量回归模型中对患者人口统计学和临床变量进行调整后,PE的前4个独立预测因素是肱骨近端骨折的初步诊断、缺铁性贫血、充血性心力衰竭和慢性肺病。其他相关危险因素包括年龄增长、肥胖、液体和电解质异常、接受全肩关节置换术而非半关节置换术以及术后护理天数。
了解这些因素可能有助于术前咨询,并证明对实施质量改进策略以减少PE的发生有用。外科医生可考虑对患有上述任何合并症的患者启动血栓预防措施。