Abdullah Kahairi, Raja Lope Ahmad Raja Ahmad, Asha'ari Zamzil Amin, Razali Mohd Sayuti, Leman Wan Islah
Department of Otolaryngology-Head & Neck Surgery, Kulliyyah of Medicine, International Islamic University Malaysia, Jalan Hospital 25100, Kuantan Pahang, Malaysia.
Malays J Med Sci. 2014 Jul;21(4):28-36.
Surgical management of head and neck cancer is undoubtedly challenging, and we would like to see the outcome of managing such cases at one of the tertiary referral center in the East Coast of Malaysia.
A 6-year retrospective analysis of surgically treated head and neck cancer cases in Hospital Tengku Ampuan Afzan (HTAA) Kuantan, Pahang was conducted.
The total number of patients reviewed was 55 and mean age of the patients was 59 years (SD 12). The larynx was the most common surgically treated site (29.1%), followed by the oral cavity (16.4%) and the paranasal sinuses (14.5%). Majority of the patients presented with stage III (32.8%) and stage IV (41.8%) cancer. Post-operative local complications (23.6%) and wound breakdown was identified as the most common cause (20%). Low hemoglobin level prior to surgery was associated with anemia after surgery (P = 0.007) and prolonged hospital stay (P = 0.030). Tumor recurrence was observed in 21.8% of the cases. Advanced stage tumor had more percentage of positive margin than early stage tumor i.e., 23% in early stage versus 58% in advanced stage (P = 0.050).
Surgical management of head and neck cancer in this center has an acceptable outcome.
头颈部癌的外科治疗无疑具有挑战性，我们希望了解马来西亚东海岸一家三级转诊中心处理此类病例的结果。
对彭亨州关丹的登古安潘·阿夫赞医院（HTAA）接受手术治疗的头颈部癌病例进行了为期6年的回顾性分析。
共审查了55例患者，患者的平均年龄为59岁（标准差12）。喉部是最常见的手术治疗部位（29.1%），其次是口腔（16.4%）和鼻窦（14.5%）。大多数患者表现为III期（32.8%）和IV期（41.8%）癌症。术后局部并发症（23.6%）和伤口裂开被确定为最常见原因（20%）。术前血红蛋白水平低与术后贫血（P = 0.007）和住院时间延长（P = 0.030）相关。21.8%的病例观察到肿瘤复发。晚期肿瘤的切缘阳性率高于早期肿瘤，即早期为23%，晚期为58%（P = 0.050）。
该中心对头颈部癌的外科治疗取得了可接受的结果。
