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高血压乳腺癌幸存者的健康行为:韩国国家健康与营养检查调查III - V(2005 - 2012)倾向分析

Health Behaviors of Breast Cancer Survivors with Hypertension: A Propensity Analysis of KNHANES III-V (2005-2012).

作者信息

Jeong Ju-Ri, Kim Sun, Jo So-Ra, Joh Ju-Youn, Kim Yeon-Pyo

机构信息

Department of Family Medicine, Hwasun Chonnam National University Hospital, Hwasun-gun, Korea; Clinic of Life After Cancer Treatment (LACT Clinic), Hwasun Chonnam National University Hospital, Hwasun-gun, Korea.

Department of Family Medicine, Hwasun Chonnam National University Hospital, Hwasun-gun, Korea.

出版信息

PLoS One. 2015 May 15;10(5):e0127346. doi: 10.1371/journal.pone.0127346. eCollection 2015.

Abstract

OBJECTIVE

This study examines health behaviors of breast cancer survivors with hypertension and compares them with those of non-cancer individuals with hypertension.

METHODS

In this cross-sectional study, a total of 10,996 hypertensive adults (≥ 19 years) who participated in the 2005-2012 Korean National Health and Nutrition Examination Survey (KNHANES) were considered. Data on alcohol consumption, smoking, physical activity, antihypertensive medication adherence, self-reported diet control, and sodium intake were collected through self-report questionnaire. A total of 64 breast cancer survivors with hypertension and 10,932 non-cancer participants with hypertension were identified. To better compare health behaviors of the two groups, 56 breast cancer survivors and 280 non-cancer participants were selected through the 1:5 nearest available matching based on estimated propensity scores. Multivariate analysis was conducted to determine any differences between the two groups.

RESULTS

According to multivariate analysis, breast cancer survivors with hypertension (n = 56) were significantly less likely to consume alcohol (odds ratio (OR): 3.75; 95% confidence interval (CI): 1.06-13.29) but significantly more likely to have sodium intake of more than 2400 mg (OR: 2.98; 95% CI: 1.27-6.97) than the propensity-matched control group (n = 280). There was no significant difference in other health behaviors between the two groups.

CONCLUSIONS

Breast cancer survivors require active interventions for healthy behaviors related to the management of comorbid conditions such as hypertension to reduce the risk of cardiovascular disease and improve their overall survival rate.

摘要

目的

本研究调查了患有高血压的乳腺癌幸存者的健康行为,并将其与患有高血压的非癌症个体的健康行为进行比较。

方法

在这项横断面研究中,纳入了参加2005 - 2012年韩国国民健康与营养检查调查(KNHANES)的总共10996名高血压成年人(≥19岁)。通过自我报告问卷收集了关于饮酒、吸烟、身体活动、抗高血压药物依从性、自我报告的饮食控制和钠摄入量的数据。共识别出64名患有高血压的乳腺癌幸存者和10932名患有高血压的非癌症参与者。为了更好地比较两组的健康行为,根据估计的倾向得分通过1:5最近邻匹配选择了56名乳腺癌幸存者和280名非癌症参与者。进行多变量分析以确定两组之间的任何差异。

结果

根据多变量分析,患有高血压的乳腺癌幸存者(n = 56)饮酒的可能性显著低于倾向匹配对照组(n = 280)(优势比(OR):3.75;95%置信区间(CI):1.06 - 13.29),但钠摄入量超过2400毫克的可能性显著高于倾向匹配对照组(OR:2.98;95% CI:1.27 - 6.97)。两组在其他健康行为方面没有显著差异。

结论

乳腺癌幸存者需要针对与高血压等合并症管理相关的健康行为进行积极干预,以降低心血管疾病风险并提高其总体生存率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/488e/4433251/91877c685cf9/pone.0127346.g001.jpg

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