Lin Jianyu
Department of Electrical and Computer Engineering, Curtin University, GPO Box U1987, Perth, Western Australia 6845, Australia.
Med Phys. 2015 May;42(5):2179-93. doi: 10.1118/1.4915535.
In multipinhole single photon emission computed tomography, the overlapping of projections has been used to increase sensitivity. Avoiding artifacts in the reconstructed image associated with projection overlaps (multiplexing) is a critical issue. In our previous report, two types of artifact-free projection overlaps, i.e., projection overlaps that do not lead to artifacts in the reconstructed image, were formally defined and proved, and were validated via simulations. In this work, a new proposition is introduced to extend the previously defined type-II artifact-free projection overlaps so that a broader range of artifact-free overlaps is accommodated. One practical purpose of the new extension is to design a baffle window multipinhole system with artifact-free projection overlaps.
First, the extended type-II artifact-free overlap was theoretically defined and proved. The new proposition accommodates the situation where the extended type-II artifact-free projection overlaps can be produced with incorrectly reconstructed portions in the reconstructed image. Next, to validate the theory, the extended-type-II artifact-free overlaps were employed in designing the multiplexing multipinhole spiral orbit imaging systems with a baffle window. Numerical validations were performed via simulations, where the corresponding 1-pinhole nonmultiplexing reconstruction results were used as the benchmark for artifact-free reconstructions. The mean square error (MSE) was the metric used for comparisons of noise-free reconstructed images. Noisy reconstructions were also performed as part of the validations.
Simulation results show that for noise-free reconstructions, the MSEs of the reconstructed images of the artifact-free multiplexing systems are very similar to those of the corresponding 1-pinhole systems. No artifacts were observed in the reconstructed images. Therefore, the testing results for artifact-free multiplexing systems designed using the extended type-II artifact-free overlaps numerically validated the developed theory.
First, the extension itself is of theoretical importance because it broadens the selection range for optimizing multiplexing multipinhole designs. Second, the extension has an immediate application: using a baffle window to design a special spiral orbit multipinhole imaging system with projection overlaps in the orbit axial direction. Such an artifact-free baffle window design makes it possible for us to image any axial portion of interest of a long object with projection overlaps to increase sensitivity.
在多针孔单光子发射计算机断层扫描中,投影重叠已被用于提高灵敏度。避免与投影重叠(复用)相关的重建图像中的伪影是一个关键问题。在我们之前的报告中,正式定义并证明了两种无伪影的投影重叠类型,即不会在重建图像中导致伪影的投影重叠,并通过模拟进行了验证。在这项工作中,引入了一个新的命题来扩展先前定义的II型无伪影投影重叠,以便容纳更广泛的无伪影重叠范围。新扩展的一个实际目的是设计一个具有无伪影投影重叠的挡板窗口多针孔系统。
首先,从理论上定义并证明了扩展的II型无伪影重叠。新命题考虑了在重建图像中可以产生扩展的II型无伪影投影重叠且带有错误重建部分的情况。接下来,为了验证该理论,在设计带有挡板窗口的复用多针孔螺旋轨道成像系统时采用了扩展的II型无伪影重叠。通过模拟进行数值验证,其中将相应的单针孔非复用重建结果用作无伪影重建的基准。均方误差(MSE)是用于比较无噪声重建图像的指标。作为验证的一部分,还进行了有噪声的重建。
模拟结果表明,对于无噪声重建,无伪影复用系统重建图像的MSE与相应的单针孔系统非常相似。在重建图像中未观察到伪影。因此,使用扩展的II型无伪影重叠设计的无伪影复用系统的测试结果在数值上验证了所发展的理论。
首先,扩展本身具有理论重要性,因为它拓宽了优化复用多针孔设计的选择范围。其次,该扩展有直接应用:使用挡板窗口设计一个在轨道轴向具有投影重叠的特殊螺旋轨道多针孔成像系统。这种无伪影的挡板窗口设计使我们能够对长物体的任何感兴趣的轴向部分进行成像,通过投影重叠提高灵敏度。