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1995 - 2009年冰岛炎症性肠病的发病率。一项基于全国人口的研究。

Incidence of inflammatory bowel disease in Iceland 1995 - 2009. A nationwide population-based study.

作者信息

Björnsson Sigurður, Tryggvason Friðrik Þór, Jónasson Jón G, Cariglia Nick, Örvar Kjartan, Kristjánsdóttir Sjöfn, Stefansson Tryggvi

机构信息

Laeknastodin, The Medical Clinic , Reykjavik , Iceland.

出版信息

Scand J Gastroenterol. 2015;50(11):1368-75. doi: 10.3109/00365521.2015.1047792. Epub 2015 May 15.

Abstract

OBJECTIVE

We analyzed the incidence of inflammatory bowel disease (IBD) in Iceland for the period 1995-2009.

MATERIAL AND METHODS

New cases of ulcerative colitis (UC) and Crohn's disease (CD) were retrieved by thorough review of all small and large intestinal pathology reports with any type of inflammation from all the pathology departments in Iceland for the period 1995-2009. All suspicious new cases of IBD were then scrutinized retrospectively by examination of their clinical records.

RESULTS

A total of 1175 cases of IBD were diagnosed, 884 UC, 279 CD and 12 IBD unclassified. The crude annual incidence of UC was 20.5/100,000, increasing from 18.1 the first 5-year period to 22.1 the last 5-year period. The crude annual incidence of CD was 6.5/100,000, 6.7 the first 5-year period and 6.6 the last 5-year period.

CONCLUSIONS

This study shows statistically significant increase in the incidence of UC during the study period. The incidence of CD has however remained stable.

摘要

目的

我们分析了1995年至2009年冰岛炎性肠病(IBD)的发病率。

材料与方法

通过全面查阅冰岛所有病理科1995年至2009年期间所有大小肠具有任何炎症类型的病理报告,检索溃疡性结肠炎(UC)和克罗恩病(CD)的新病例。然后通过检查其临床记录对所有可疑的IBD新病例进行回顾性审查。

结果

共诊断出1175例IBD病例,其中884例为UC,279例为CD,12例为未分类的IBD。UC的粗年发病率为20.5/10万,从前5年的18.1上升至最后5年的22.1。CD的粗年发病率为6.5/10万,前5年为6.7,最后5年为6.6。

结论

本研究表明,在研究期间UC的发病率有统计学意义的增加。然而,CD的发病率保持稳定。

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