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炎症性肠病不断演变的流行病学

Evolving Epidemiology of IBD.

作者信息

Windsor Joseph W, Kaplan Gilaad G

机构信息

Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Teaching Research and Wellness Building 3D03-18, 3280 Hospital Drive NW, Calgary, Alberta, T2N 4Z6, Canada.

Department of Medicine, Cumming School of Medicine, University of Calgary, Teaching Research and Wellness Building 3D03-18, 3280 Hospital Drive NW, Calgary, Alberta, T2N 4Z6, Canada.

出版信息

Curr Gastroenterol Rep. 2019 Jul 23;21(8):40. doi: 10.1007/s11894-019-0705-6.

Abstract

PURPOSE OF REVIEW

Once thought a disease of Western civilizations, the inflammatory bowel diseases (IBD) impose a global burden, now penetrating populations in Asia, Africa, and South America. We summarize similarities and differences in the epidemiology of IBD globally, highlighting gaps in knowledge where future study is needed.

RECENT FINDINGS

While incidence of IBD is stabilizing (or even decreasing) in many westernized regions, prevalence continues to grow due to a young age of onset and low mortality. In newly westernized regions, IBD is beginning to penetrate populations comparable to the rapid increases seen in North America, Europe, and Oceania in the last century. IBD imposes a significant fiscal and resource burden on healthcare systems. As global prevalence of these diseases continues to increase, we desperately need to anticipate the future burden to proactively prepare our healthcare systems for the challenges of increased patient load and aging populations with comorbid conditions and longer disease course.

摘要

综述目的

炎症性肠病(IBD)曾被认为是西方文明特有的疾病,如今却给全球带来了负担,目前已蔓延至亚洲、非洲和南美洲的人群。我们总结了全球IBD流行病学的异同,突出了未来研究所需的知识空白。

最新发现

在许多西方化地区,IBD的发病率正在趋于稳定(甚至下降),但由于发病年龄较轻且死亡率较低,患病率仍在持续上升。在新近西方化的地区,IBD开始在人群中蔓延,其速度与北美、欧洲和大洋洲上世纪的快速增长相当。IBD给医疗系统带来了巨大的财政和资源负担。随着这些疾病在全球的患病率持续上升,我们迫切需要预测未来的负担,以便积极为医疗系统应对患者数量增加、人口老龄化以及合并症和疾病病程延长等挑战做好准备。

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