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评估一项降低重症监护病房(ICU)机械通气患者潮气量的干预措施。

Evaluation of an intervention to reduce tidal volumes in ventilated ICU patients.

作者信息

Bourdeaux C P, Birnie K, Trickey A, Thomas M J C, Sterne J, Donovan J L, Benger J, Brandling J, Gould T H

机构信息

Intensive Care Unit, Queens Building, University Hospitals Bristol, Upper Maudlin Street, Bristol BS2 8HW, UK

School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Clifton, Bristol BS8 2PS, UK.

出版信息

Br J Anaesth. 2015 Aug;115(2):244-51. doi: 10.1093/bja/aev110. Epub 2015 May 15.

Abstract

BACKGROUND

There is considerable evidence that the use of tidal volumes <6 ml kg(-1) predicted body weight (PBW) reduces mortality in mechanically ventilated patients. We evaluated the effectiveness of using a large screen displaying delivered tidal volume in ml kg(-1) (PBW) for reducing tidal volumes.

METHODS

We assessed the intervention in two 6-month periods. A qualitative study was undertaken after the intervention period to examine staff interaction with the intervention. The study was conducted in a mixed medical and surgical intensive care unit at University Hospitals Bristol, UK. Consecutive patients requiring controlled mechanical ventilation for more than 1 h were included. Alerts were triggered when tidal volume breached predetermined targets and these alerts were visible to ICU clinicians in real time.

RESULTS

A total of 199 patients with 7640 h of data were observed during the control time period and 249 patients with 10 656 h of data were observed in the intervention period. Time spent with tidal volumes <6 ml kg(-1) PBW increased from 17.5 to 28.6% of the period of controlled mechanical ventilation. Time spent with a tidal volume <8 ml kg(-1) PBW increased from 60.6 to 73.9%. The screens were acceptable to staff and stimulated an increase in attendance of clinicians at the bedside to adjust ventilators.

CONCLUSIONS

Changing the format of data and displaying it with real-time alerts reduced delivered tidal volumes. Configuring information in a format more likely to result in desired outcomes has the potential to improve the translation of evidence into practice.

摘要

背景

有大量证据表明,使用低于预测体重(PBW)6 ml/kg的潮气量可降低机械通气患者的死亡率。我们评估了使用大屏幕以毫升/千克(PBW)为单位显示输送潮气量对减少潮气量的有效性。

方法

我们在两个6个月的时间段内评估了该干预措施。在干预期后进行了一项定性研究,以检查工作人员与该干预措施的互动情况。该研究在英国布里斯托尔大学医院的内科和外科混合重症监护病房进行。纳入连续需要控制机械通气超过1小时的患者。当潮气量超过预定目标时会触发警报,重症监护病房的临床医生可实时看到这些警报。

结果

在对照时间段内共观察了199例患者,有7640小时的数据,在干预期观察了249例患者,有10656小时的数据。潮气量低于6 ml/kg PBW的时间占控制机械通气时间的比例从17.5%增加到28.6%。潮气量低于8 ml/kg PBW的时间占比从60.6%增加到73.9%。工作人员对这些屏幕表示认可,并且促使临床医生到床边调整呼吸机的次数增加。

结论

改变数据格式并实时显示警报可降低输送的潮气量。以更有可能产生预期结果的格式配置信息有可能改善将证据转化为实践的情况。

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