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球孢子菌病迟发型超敏皮肤试验的重现。

The Return of Delayed-Type Hypersensitivity Skin Testing for Coccidioidomycosis.

机构信息

Valley Fever Center for Excellence.

University of Arizona College of Medicine Southern Arizona Veterans Affairs Health Care System, Tucson.

出版信息

Clin Infect Dis. 2015 Sep 1;61(5):787-91. doi: 10.1093/cid/civ388. Epub 2015 May 15.

DOI:10.1093/cid/civ388
PMID:25979308
Abstract

A skin test that detects dermal hypersensitivity in persons with past infection with Coccidioides species is again available for clinical use. Nearly all of the clinical studies with similar materials were published prior to the 1990s, and as a result, many practicing physicians will be unfamiliar with how skin testing for coccidioidomycosis might be useful in patient management or as a research tool. We review clinical and epidemiological studies with past skin test antigens, the composition of past and current skin test preparations with particular attention to differences in the preservatives, and how the current preparation could be used today.

摘要

一种可检测出过去感染过粗球孢子菌物种的人皮肤过敏的皮肤测试再次可用于临床应用。几乎所有使用类似材料的临床研究都是在 20 世纪 90 年代之前发表的,因此,许多执业医生将不熟悉如何使用球孢子菌病皮肤测试来管理患者或作为研究工具。我们回顾了过去的皮肤测试抗原的临床和流行病学研究,过去和当前的皮肤测试制剂的组成,特别注意防腐剂的差异,以及当前制剂今天如何使用。

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