头颈部癌症的放射治疗。

Radiation treatment of head and neck cancer.

作者信息

Yom Sue S

机构信息

Department of Radiation Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, Box 1708, 1600 Divisadero Street, MZ Building R H1031, San Francisco, CA 94143-1708, USA.

出版信息

Surg Oncol Clin N Am. 2015 Jul;24(3):423-36. doi: 10.1016/j.soc.2015.03.015.

DOI:10.1016/j.soc.2015.03.015

PMID:25979392

Abstract

Radiation therapy plays a central and continuously evolving role in the treatment of head and neck cancer. In this review, some basic principles of radiation oncology are explained and common clinical scenarios are addressed in which radiation therapy forms part of the treatment course, with a focus on issues most pertinent to the interaction of radiation oncology with surgical treatment. These issues include refinement of the indications guiding the choice of adjuvant radiation therapy or chemoradiotherapy, sequencing and timing of therapies before or after definitive surgical management, and scientific and technical advances with the potential to reduce radiation-related toxicity.

摘要

放射治疗在头颈癌的治疗中发挥着核心且不断发展的作用。在本综述中，解释了放射肿瘤学的一些基本原则，并阐述了放射治疗作为治疗过程一部分的常见临床情况，重点关注与放射肿瘤学和外科治疗相互作用最相关的问题。这些问题包括指导辅助放疗或放化疗选择的适应证细化、确定性手术治疗前后治疗的顺序和时机，以及有可能降低放疗相关毒性的科学技术进展。