Morara S, Provini L, Rosina A
Istituto di Fisiologia dei Centri Nervosi del CNR, Milano, Italy.
Brain Res. 1989 Dec 18;504(2):315-9. doi: 10.1016/0006-8993(89)91376-0.
CGRP-like immunoreactivity was studied in the cerebellar cortex and precerebellar nuclei of neonatal rats. From postnatal day (PD) 0 to PD 13-15, CGRP immunoreactivity was transiently found in fiber-like structures around Purkinje cells, defining parasagittal bands. Following the same time course, transient labeling was also found in the inferior olive neurons which, in the adult, distribute their axons to the olivocerebellar compartments corresponding to the immunoreactive bands. It is concluded that CGRP is transiently expressed in specific climbing fiber compartments.
在新生大鼠的小脑皮质和小脑前核中研究了降钙素基因相关肽（CGRP）样免疫反应性。从出生后第0天到出生后第13 - 15天，在浦肯野细胞周围的纤维样结构中短暂发现CGRP免疫反应性，形成矢状旁带。在相同的时间进程中，在下橄榄核神经元中也发现了短暂标记，在成体中，这些神经元将其轴突分布到与免疫反应带相对应的橄榄小脑区。得出的结论是，CGRP在特定的攀缘纤维区短暂表达。
