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超级肥胖患者行腹腔镜Roux-en-Y胃旁路手术的疗效

Outcomes of laparoscopic Roux-en-Y gastric bypass in super-super-obese patients.

作者信息

Mehaffey J Hunter, LaPar Damien J, Turrentine Florence E, Miller Michael S, Hallowell Peter T, Schirmer Bruce D

机构信息

Department of Surgery, University of Virginia, Charlottesville, Virginia.

Department of Surgery, University of Virginia, Charlottesville, Virginia.

出版信息

Surg Obes Relat Dis. 2015 Jul-Aug;11(4):814-9. doi: 10.1016/j.soard.2014.11.027. Epub 2014 Dec 8.

Abstract

BACKGROUND

There is limited outcome data for super-super-obese (SSO) patients, those with Body Mass Index (BMI) ≥ 60 kg/m(2), who seek surgical treatment with Laparoscopic Roux-en-Y Gastric Bypass (LRYGB). A large single center LRYGB experience was reviewed to compare the safety and efficacy of LRYGB in SSO patients to the standard obese population undergoing this procedure.

METHODS

The American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database and an Institutional Review Board approved prospective database was used to identify all patients undergoing LRYGB by multiple surgeons at a single institution between 1/1/1994 and 11/15/2013. Preoperative co-morbidities, postoperative complications, 30-day outcomes, and weight loss at yearly intervals were analyzed to determine difference between SSO patients and NonSSO patients (BMI < 60 kg/m(2)).

RESULTS

Of the 2009 patients undergoing LRYGB over the past 20 years; 328 had BMI ≥ 60 kg/m(2). Preoperative co-morbidities, conversion to open, and length of stay were significantly increased among SSO patients; however there was no significant difference in postoperative outcomes or complications. Percent reduction of excess BMI beyond 12 months was significantly improved among NonSSO patients with less than 30% follow-up beyond 2 years.

CONCLUSIONS

LRYGB appears well tolerated for super-super-obese patients with BMI ≥ 60 kg/m(2) in experienced centers. These patients still have significant reduction in excess BMI despite being less than NonSSO patients undergoing RYGB. The ACS NSQIP database provides excellent tracking of institutional progress with bariatric surgical outcomes to facilitate the improvement of best practice techniques.

摘要

背景

对于寻求腹腔镜Roux-en-Y胃旁路术(LRYGB)手术治疗的超级肥胖(SSO)患者,即体重指数(BMI)≥60kg/m²的患者,其预后数据有限。回顾了一个大型单中心LRYGB经验,以比较LRYGB在SSO患者与接受该手术的标准肥胖人群中的安全性和有效性。

方法

使用美国外科医师学会国家外科质量改进计划(ACS NSQIP)数据库和一个经机构审查委员会批准的前瞻性数据库,确定1994年1月1日至2013年11月15日期间在单一机构由多位外科医生进行LRYGB手术的所有患者。分析术前合并症、术后并发症、30天预后以及每年的体重减轻情况,以确定SSO患者与非SSO患者(BMI<60kg/m²)之间的差异。

结果

在过去20年接受LRYGB手术的2009例患者中,328例BMI≥60kg/m²。SSO患者术前合并症、转为开放手术以及住院时间显著增加;然而,术后预后或并发症无显著差异。随访超过2年的非SSO患者中,12个月后多余BMI的降低百分比显著改善,随访率低于30%。

结论

在经验丰富的中心,LRYGB似乎对BMI≥60kg/m²的超级肥胖患者耐受性良好。尽管这些患者多余BMI的降低幅度小于接受RYGB手术的非SSO患者,但仍有显著降低。ACS NSQIP数据库为肥胖手术预后的机构进展提供了出色的跟踪,以促进最佳实践技术的改进。

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