Schwab Fabienne D, Zettler Eva K, Moh Andala, Schötzau Andreas, Gross Uwe, Günthert Andreas R
J Perinat Med. 2016 Jul 1;44(5):511-5. doi: 10.1515/jpm-2015-0004.
To assess the risk for preterm deliveries <37 week of gestation and associated prevalence of vaginal infection in a rural setting after the tsunami in Banda Aceh, Indonesia.
Wet mount microscopy, vaginal pH and vaginal swabs for microbiological culture were collected in pregnant women during the 2nd trimester from February to June of 2005 in four temporary outpatient clinics and the patients were followed up until delivery.
One hundred and fifty-nine pregnant patients were screened. Sixty-two could be followed up until delivery. Thirty-nine (62.9%) delivered at term and 23 (37.1%) delivered prematurely. Significant risk factors for preterm delivery were a history of preterm delivery and group B streptococcus infection. Increased vaginal pH alone had no significant influence on preterm delivery, although there was a trend.
The rate of preterm delivery was high in this cohort. We suggest risk stratification for preterm delivery in rural conditions by performing a vaginal pH and wet mount microscopy. If either is suspect we suggest collecting a vaginal swab for microbiological culture for targeted treatment. Patients with a history of preterm delivery are at increased risk and should be monitored closely.
评估印度尼西亚班达亚齐海啸后农村地区妊娠<37周早产的风险及阴道感染的相关患病率。
2005年2月至6月妊娠中期，在四个临时门诊为孕妇采集湿片显微镜检查样本、检测阴道pH值并采集阴道拭子进行微生物培养，对患者进行随访直至分娩。
共筛查了159名孕妇，其中62名随访至分娩。39名（62.9%）足月分娩，23名（37.1%）早产。早产的显著危险因素是早产史和B族链球菌感染。单独的阴道pH值升高对早产虽有一定趋势但无显著影响。
该队列中早产率较高。我们建议通过检测阴道pH值和进行湿片显微镜检查，对农村地区的早产风险进行分层。如果其中任何一项可疑，建议采集阴道拭子进行微生物培养以进行针对性治疗。有早产史的患者风险增加，应密切监测。
