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青少年与成年患者早产情况的差异

Difference between Preterm Birth in Adolescent and Adult Patients.

作者信息

Uzunov Ana Veronica, Secara Diana Cristina, Constantin Andreea Elena, Mehedintu Claudia, Cirstoiu Monica Mihaela

机构信息

Doctoral School of "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

出版信息

Maedica (Bucur). 2022 Dec;17(4):789-794. doi: 10.26574/maedica.2022.17.4.789.

DOI:10.26574/maedica.2022.17.4.789
PMID:36818249
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9923062/
Abstract

Preterm delivery represents an important public health problem due to its neonatal outcomes. There are numerous complications that occur due to prematurity, but the most significant one is represented by neonatal death. Even if the certain mechanism of prematurity is elusive, there are various risk factors known to be involved in the etiology of preterm birth, among which one is young age. The present study aims to find whether preterm delivery has a higher rate in adolescent patients and if neonatal outcomes are different in adolescent and adult patients. We performed an observational retrospective study about preterm infants from adolescent and adult patients. Thus, we analyzed 96 patients aged between 13 and 38 years who delivered in our unit between October 1st 2018 and December 31st 2021. Patients were divided into two groups: a study group (n=59), which included adolescents who delivered preterm, and a control group (n=37), which comprised adult patients who delivered preterm. We evaluated the rate of prematurity of all births and among patients enrolled in the present study and the neonatal outcome by newborn's weight, one-minute newborn's Apgar score and Neonatal Intensive Care Unit (NICU) admission. In our study, the rate of prematurity was higher in adolescent patients, with a rate of 61.46%. The newborns' outcomes, analyzed by newborn's weight and one-minute Apgar score, were better in adolescent patients compared to adult ones. Therefore, newborns from adult patients needed neonatal intensive care more often, with a rate of 62.16%, while in the study group the percentage was 38.98%. The rate of antenatal care was higher in adult patients compared to adolescent ones (32.43% 27.12%). Adolescents have a higher risk of preterm delivery; however, their newborns have better outcomes than those of adult patients. The lack of antenatal care represents a risk factor for preterm delivery.

摘要

由于早产的新生儿结局,早产是一个重要的公共卫生问题。早产会引发众多并发症,但最严重的是新生儿死亡。即便早产的确切机制尚不明确,但已知多种风险因素与早产的病因有关,其中之一是年轻。本研究旨在探究青少年患者中早产发生率是否更高,以及青少年和成年患者的新生儿结局是否存在差异。我们针对青少年和成年患者的早产婴儿进行了一项观察性回顾研究。为此,我们分析了2018年10月1日至2021年12月31日期间在我院分娩的96例年龄在13至38岁之间的患者。患者被分为两组:研究组(n = 59),包括早产的青少年;对照组(n = 37),由早产的成年患者组成。我们通过新生儿体重、新生儿1分钟阿氏评分和新生儿重症监护病房(NICU)收治情况评估了所有分娩以及本研究纳入患者的早产发生率和新生儿结局。在我们的研究中,青少年患者的早产发生率更高,为61.46%。按新生儿体重和1分钟阿氏评分分析,青少年患者的新生儿结局优于成年患者。因此,成年患者的新生儿更常需要新生儿重症监护,发生率为62.16%,而研究组的这一比例为38.98%。成年患者的产前检查率高于青少年患者(32.43%对27.12%)。青少年早产风险更高;然而,他们的新生儿结局比成年患者的更好。缺乏产前检查是早产的一个风险因素。

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本文引用的文献

1
Association between Maternal Factors, Preterm Birth, and Low Birth Weight of Chilean Singletons.智利单胎妊娠产妇因素、早产与低出生体重之间的关联
Children (Basel). 2022 Jun 28;9(7):967. doi: 10.3390/children9070967.
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