Helfenstein-Didier C, Tanter M, Gennisson J-L, Beillas P
Université de Lyon, F--69622 Lyon, France; Université Claude Bernard Lyon 1, Villeurbanne, France; IFSTTAR, UMR_T9406, LBMC Laboratoire de Biomécanique et Mécanique des Chocs, F-69675 Bron, France.
Institut Langevin - Ondes et Images, ESPCI ParisTech, PSL Research University, CNRS UMR7587, INSERM U979, 1 rue Jussieu, 75238 Paris Cedex, France.
J Biomech. 2015 Jul 16;48(10):1852-9. doi: 10.1016/j.jbiomech.2015.04.033. Epub 2015 May 2.
A protocol based on ultrafast ultrasonography was developed to study the internal response of isolated perfused human (n=3) and porcine (n=11) kidneys subjected to loading at 0.003 m/s and 0.3m/s respectively. Regional uniaxial strains were calculated based on natural target tracking. The effect of loading speed and regional differences could be statistically detected on the porcine specimens. However, despite the inhomogeneity of their anatomical structures, strains' responses appeared relatively homogeneous at 0.3m/s in both porcine and human kidneys. Failure, identified as a sudden change on the ultrasonography movie, also appeared at similar compression levels for both species (38.3% of applied strain in average for human and 35.8% of applied strain in average for porcine).
开发了一种基于超快超声检查的方案，以研究分别以0.003米/秒和0.3米/秒的速度加载的离体灌注人肾（n = 3）和猪肾（n = 11）的内部反应。基于自然目标跟踪计算局部单轴应变。在猪标本上可以通过统计学方法检测加载速度和区域差异的影响。然而，尽管其解剖结构不均匀，但在0.3米/秒的速度下，猪肾和人肾的应变反应相对均匀。超声检查电影中显示的突然变化被确定为衰竭，两种物种在相似的压缩水平下也出现了衰竭（人平均为施加应变的38.3%，猪平均为施加应变的35.8%）。
