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儿科起搏25年的并发症与风险评估

Complications and Risk Assessment of 25 Years in Pediatric Pacing.

作者信息

Wilhelm B Jakub, Thöne Marc, El-Scheich Tarik, Livert David, Angelico Richard, Osswald Brigitte

机构信息

Easton Hospital, Department of Surgery, Drexel University College of Medicine, Easton, Pennsylvania; Division of Cardiovascular Surgery, Heinrich Heine University Hospital Düsseldorf, Düsseldorf, Germany.

Division of Cardiovascular Surgery, Heinrich Heine University Hospital Düsseldorf, Düsseldorf, Germany.

出版信息

Ann Thorac Surg. 2015 Jul;100(1):147-53. doi: 10.1016/j.athoracsur.2014.12.098. Epub 2015 May 14.

Abstract

BACKGROUND

Children who require cardiac pacemaker implantation have presented a small patient sub-population since the breakthrough of this technology in the 1950s and 1960s. Their small bodies result in a technical challenge for the operating surgeon and put the patient at risk for a series of specific complications. Our study aims to analyze complications and to identify risk factors of endocardial and epicardial pacemaker systems in children.

METHODS

All pacemaker-related operations in pediatric patients up to the age of 18 years from 1985 through 2010 were retrospectively evaluated. Demographic data including age, height, and weight were recorded. Idiopathic and postoperative dysrhythmias were analyzed separately.

RESULTS

A total of 149 pacemaker operations were performed in 73 patients. Thirty-two patients did not have a previous cardiac operation. Indications for revision included box exchange, lead-related problems, pacemaker pocket complications, impaired left ventricular function, and pectoral muscle stimulation. Increased pacing thresholds occurred in 17.2% of the patients with epicardial leads compared with 2.9% in the endocardial group. Aside from threshold-related revision, lead problems are more common in the endocardial group (30.4% vs 17.2%). Venous thrombosis occurred in 13.7% of the patients (only endocardial), preferentially (25%) in the weight group less than 15 kg and in idiopathic patients (15.6% vs 10.5% with prior cardiac surgery).

CONCLUSIONS

Cardiac pacing is particularly challenging in the pediatric patient population facing a large number of reoperations during their lifetime. The lack of clear superiority of either epicardial or endocardial pacing systems requires an individual concept.

摘要

背景

自20世纪50年代和60年代心脏起搏器植入技术取得突破以来,需要植入心脏起搏器的儿童一直是一个小患者亚群。他们体型小给手术医生带来技术挑战,并使患者面临一系列特定并发症的风险。我们的研究旨在分析并发症,并确定儿童心内膜和心外膜起搏器系统的危险因素。

方法

回顾性评估1985年至2010年期间18岁以下儿科患者所有与起搏器相关的手术。记录包括年龄、身高和体重在内的人口统计学数据。对特发性和术后心律失常分别进行分析。

结果

73例患者共进行了149次起搏器手术。32例患者此前未进行过心脏手术。翻修的适应症包括起搏器盒更换、导线相关问题、起搏器囊袋并发症、左心室功能受损和胸肌刺激。心外膜导线患者中17.2%出现起搏阈值升高,而心内膜组为2.9%。除了与阈值相关的翻修外,导线问题在心内膜组更常见(30.4%对17.2%)。13.7%的患者发生静脉血栓形成(仅心内膜),在体重小于15kg的患者组和特发性患者中更易发生(25%)(有心脏手术史者为15.6%对10.5%)。

结论

在儿科患者群体中,心脏起搏尤其具有挑战性,他们一生中需要进行大量再次手术。心外膜或心内膜起搏系统缺乏明显优势,需要个体化方案。

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