全髋关节置换术治疗强直性脊柱炎患者：术后是否需要放疗预防异位骨化？
Total Hip Arthroplasty for Patients Who Have Ankylosing Spondylitis: Is Postoperative Irradiation Required for Prophylaxis of Heterotopic Ossification?
机构信息
Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Orthopaedic, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Orthopaedic, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
出版信息
J Arthroplasty. 2015 Oct;30(10):1752-6. doi: 10.1016/j.arth.2015.04.022. Epub 2015 Apr 24.
Postoperative radiation for prevention of heterotopic ossification (HO) has been proven effective for the patients with ankylosing spondylitis (AS) after total hip arthroplasties (THA). This study aims to evaluate the effect of postoperative radiation in HO formation following THA in patients with AS. We retrospectively reviewed 129 hips from 91 patients with AS receiving primary THA from July 2004 to December 2012. There were total 38 patients (53 hips) did not receive postoperative prophylaxis in Group I. Moreover, 53 patients (76 hips) received postoperative single-fraction radiotherapy of 500 cGy in Group II. After a minimum 12-month follow-up, there was no significant difference in HO formation between the two groups (P=0.210). This study suggests that postoperative radiation may not be necessary in Asian patients.
术后放疗预防异位骨化（HO）已被证明对强直性脊柱炎（AS）全髋关节置换术后患者有效。本研究旨在评估术后放疗对 AS 患者全髋关节置换术后 HO 形成的影响。我们回顾性分析了 2004 年 7 月至 2012 年 12 月期间接受初次全髋关节置换术的 91 例 AS 患者的 129 髋。其中，I 组有 38 例（53 髋）未接受术后预防治疗，II 组 53 例（76 髋）接受术后单次 500cGy 放疗。两组患者均至少随访 12 个月，HO 形成无显著差异（P=0.210）。本研究表明，术后放疗对于亚洲患者可能并非必要。
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