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普尔夏视网膜病变:治疗还是不治疗?

Purtscher retinopathy: to treat or not to treat?

作者信息

Gil Pedro, Pires Joana, Costa Esmeralda, Matos Rita, Cardoso Mariana Sá, Mariano Manuel

机构信息

Centro Hospitalar Baixo Vouga, Aveiro - Portugal.

Centro Hospitalar Universitário de Coimbra, Coimbra - Portugal.

出版信息

Eur J Ophthalmol. 2015 Oct 21;25(6):e112-5. doi: 10.5301/ejo.5000623.

Abstract

PURPOSE

To report a case of Purtscher retinopathy and its therapeutic approach.

METHODS

In this observational case report, complete ophthalmologic examination was performed, including best-corrected visual acuity (BCVA) testing, slit-lamp biomicroscopy, dilated fundus examination, spectral-domain optical coherence tomography (OCT), fluorescein angiography (FA), and Humphrey 24-2 visual field testing.

RESULTS

The patient complained of right eye diminished visual acuity 48 hours after a car accident, with severe thoracic and abdominal blunt trauma but no direct ocular trauma. The BCVA was counting fingers at 1 meter, anterior segment examination was unremarkable, and the fundus showed cotton-wool spots and Purtscher flecken. Macular OCT revealed subretinal fluid with neurosensorial retinal detachment. The FA showed peripapillary and parafoveal leakage and visual field testing presented a central scotoma. We opted for an observation-only approach. Follow-up revealed a progressive reabsorption of the subretinal fluid with complete resolution of the macular neurosensorial retinal detachment after 2 weeks. After 2 months of follow-up, BCVA was 20/25 and the OCT revealed atrophic changes, with no subretinal fluid. The favorable outcome in terms of BCVA persisted at 4 and 6 months follow-up, although the central scotoma did not improve significantly.

CONCLUSIONS

The characterization of both acute and late-stage lesions provides a valuable insight to a better characterization of this rare disease. Despite a favorable response with a conservative therapeutic approach, structural and functional late stage sequelae influence the final visual outcome.

摘要

目的

报告一例普尔夏视网膜病变及其治疗方法。

方法

在本观察性病例报告中,进行了全面的眼科检查,包括最佳矫正视力(BCVA)测试、裂隙灯生物显微镜检查、散瞳眼底检查、光谱域光学相干断层扫描(OCT)、荧光素血管造影(FA)和 Humphrey 24-2 视野测试。

结果

患者在车祸后 48 小时主诉右眼视力下降,伴有严重的胸腹部钝性创伤,但无直接眼部创伤。BCVA 为 1 米数指,眼前节检查无异常,眼底可见棉絮斑和普尔夏斑。黄斑 OCT 显示视网膜下液伴神经感觉层视网膜脱离。FA 显示视乳头周围和黄斑旁渗漏,视野测试显示中心暗点。我们选择了仅观察的方法。随访发现视网膜下液逐渐吸收,2 周后黄斑神经感觉层视网膜脱离完全消退。随访 2 个月后,BCVA 为 20/25,OCT 显示萎缩性改变,无视网膜下液。尽管中心暗点无明显改善,但在 4 个月和 6 个月随访时 BCVA 仍保持良好结果。

结论

对急性和晚期病变的特征描述为更好地认识这种罕见疾病提供了有价值的见解。尽管保守治疗方法取得了良好效果,但晚期的结构和功能后遗症会影响最终的视力结果。

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