Rotuski Grzegorz, Bojarska Magdalena, Patyk Michał, Różycki Radosław, Gołębiewska Joanna
Department of Ophthalmology, Military Institute of Aviation Medicine, 01-755 Warsaw, Poland.
Diagnostics (Basel). 2024 Jul 10;14(14):1476. doi: 10.3390/diagnostics14141476.
Purtscher retinopathy is a rare but severe sight-threatening eye condition that mostly occurs in middle-aged men after chest compression or head injury. In cases such as acute pancreatitis, connective tissue disorders, kidney failure or COVID-19 infection with similar ocular findings but no history of trauma, a diagnosis of Purtscher-like retinopathy is made. We present a case of a 72-year-old female with typical symptoms of Purtscher retinopathy in both eyes after a car crash accident. Although the pathophysiology of the disease is not fully understood, the main cause of Purtscher retinopathy seems to be an embolic occlusion of the precapillary arterioles which supply the superficial peripapillary capillaries. Activation of the C5a component of the complement predisposes the leukocytes to aggregation, which obstructs blood flow. The main symptom of Purtscher retinopathy is sudden, painless deterioration of vision which occurs up to 48 h after the injury. In most patients, the changes observed in the fundus of the eye resolve within several months, and visual acuity slowly improves, sometimes even returning to the state from before the injury. However, risk factors such as older age, high hyperopia, and late treatment implementation can make the prognosis less favorable.
普尔夏视网膜病变是一种罕见但严重的威胁视力的眼部疾病,多见于中年男性,常发生于胸部受压或头部受伤后。在急性胰腺炎、结缔组织病、肾衰竭或新冠病毒感染等情况下,若出现类似眼部表现但无外伤史,则诊断为类普尔夏视网膜病变。我们报告一例72岁女性,在车祸后双眼出现典型的普尔夏视网膜病变症状。尽管该病的病理生理学尚未完全明确,但普尔夏视网膜病变的主要原因似乎是供应视乳头周围浅层毛细血管的毛细血管前小动脉发生栓塞性阻塞。补体C5a成分的激活使白细胞易于聚集,从而阻碍血流。普尔夏视网膜病变的主要症状是受伤后48小时内视力突然无痛性下降。大多数患者眼底观察到的变化在数月内消退,视力缓慢改善,有时甚至恢复到受伤前的状态。然而,年龄较大、高度远视和治疗实施较晚等危险因素会使预后较差。