Saenz A, Bakchine S, Jonin P-Y, Ehrlé N
Laboratoire de neurosciences fonctionnelles et pathologies, EA 4559, université de Lille - Nord de France, UFR de psychologie, Pont-de-Bois, BP 60149, 59653 Villeneuve-d'Ascq cedex, France; Service de neurologie, hôpital Maison-Blanche, CHU de Reims, 45, rue Cognacq-Jay, 51092 Reims cedex, France.
Service de neurologie, hôpital Maison-Blanche, CHU de Reims, 45, rue Cognacq-Jay, 51092 Reims cedex, France.
Rev Neurol (Paris). 2015 Sep;171(8-9):624-45. doi: 10.1016/j.neurol.2015.02.014. Epub 2015 May 14.
Memory impairment, especially verbal episodic memory (VEM), represents a common ground for cognitive complaint in patients with multiple sclerosis (MS). Beyond the difficulty caused in daily life, these deficits may impact on occupational activities. Neuropsychological assessment of these patients has to include VEM tests, to describe the level of dysfunction of the different processes contributing to VEM and, if required, to guide adapted cognitive rehabilitation. The objective of the present paper is to propose a critique review of the literature on VEM abilities in MS. This review will present the conceptual references and the psychometric characteristics of the main VEM tests applied in MS (isolated tests or included within more general batteries developed specifically for MS). In a second phase, we propose an inventory of work on MS presented as a function of the cognitive processes involved. This approach provides an approach to the limitations of each conception and possible terminological ambiguities. Contributions to knowledge of MS memory impairments will be clarified, as well as the impact of the disease characteristics (MS forms, disease duration, EDSS).
记忆障碍,尤其是言语情景记忆(VEM),是多发性硬化症(MS)患者认知功能障碍的常见表现。除了给日常生活带来不便外,这些缺陷还可能影响职业活动。对这些患者进行神经心理学评估时必须包括VEM测试,以描述导致VEM的不同过程的功能障碍程度,并在需要时指导适应性认知康复。本文的目的是对MS患者VEM能力的文献进行批判性综述。本综述将介绍MS中应用的主要VEM测试的概念依据和心理测量特征(单独测试或包含在专门为MS开发的更通用的测试组合中)。在第二阶段,我们提出了一份关于MS研究的清单,该清单是根据所涉及的认知过程来呈现的。这种方法有助于了解每个概念的局限性以及可能存在的术语歧义。同时,还将阐明对MS记忆障碍知识的贡献,以及疾病特征(MS类型、病程、扩展残疾状态量表)的影响。