Kusztal Mariusz, Dzierżek Przemysław, Gołębiowski Tomasz, Weyde Wacław, Klinger Marian
Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland.
Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland; Faculty of Dentistry, Wroclaw Medical University, Wroclaw, Poland.
Postepy Hig Med Dosw (Online). 2015 May 17;69:633-7. doi: 10.5604/17322693.1153074.
Bioelectrical impedance analysis (BIA) is an affordable, non-invasive and fast alternative method to assess body composition. The purpose of this study was to compare two different tetrapolar BIA devices for estimating body fluid volumes and body cell mass (BCM) in a clinical setting among patients with kidney failure.
All double measurements were performed by multi-frequency (MF) and single-frequency (SF) BIA analyzers: a Body Composition Monitor (Fresenius Medical Care, Germany) and BIA-101 (Akern, Italy), respectively. All procedures were conducted according to the manufacturers' instructions (dedicated electrodes, measurement sites, positions, etc). Total body water (TBW), extracellular water (ECW), intracellular water (ICW) and BCM were compared. The study included 39 chronic kidney disease patients (stage III-V) with a mean age of 45.8 ± 8 years (21 men and 18 women) who had a wide range of BMI [17-34 kg/m2 (mean 26.6 ±5)].
A comparison of results from patients with BMI <25 vs ≥25 revealed a significant discrepancy in measurements between the two BIA devices. Namely, in the group with BMI <25 (n=16) acceptable correlations were obtained in TBW (r 0.99; p<0.01), ICW (0.92; p<0.01), BCM (0.68; p<0.01), and ECW (0.96 p<0.05), but those with BMI ≥25 (n=23) showed a discrepancy (lower correlations) in TBW (r 0.82; p<0.05), ICW (0.78; p<0.05), BCM (0.52; p<0.05), and ECW (0.76; p<0.01).
Since estimates of TBW, ICW and BCM by the present BIA devices do not differ in patients with BMI <25, they might be interchangeable. This does not hold true for overweight/obese renal patients.
生物电阻抗分析（BIA）是一种经济实惠、非侵入性且快速的评估身体成分的替代方法。本研究的目的是比较两种不同的四极BIA设备在临床环境中对肾衰竭患者体液量和身体细胞质量（BCM）的估计。
所有双次测量分别由多频（MF）和单频（SF）BIA分析仪进行：分别为身体成分监测仪（德国费森尤斯医疗）和BIA - 101（意大利阿克恩）。所有程序均按照制造商的说明（专用电极、测量部位、姿势等）进行。比较了总体水（TBW）、细胞外液（ECW）、细胞内液（ICW）和BCM。该研究纳入了39例慢性肾脏病患者（III - V期），平均年龄为45.8±8岁（21名男性和18名女性），其体重指数范围较广[17 - 34 kg/m²（平均26.6±5）]。
对体重指数<25与≥25的患者结果进行比较，发现两种BIA设备的测量结果存在显著差异。具体而言，在体重指数<25的组（n = 16）中，TBW（r 0.99；p<0.01）、ICW（0.92；p<0.01）、BCM（0.68；p<0.01）和ECW（0.96；p<0.05）获得了可接受的相关性，但体重指数≥25的组（n = （此处原文有误，应为23））在TBW（r 0.82；p<0.05）、ICW（0.78；p<0.05）、BCM（0.52；p<0.05）和ECW（0.76；p<0.01）方面存在差异（相关性较低）。
由于当前BIA设备对体重指数<25的患者的TBW、ICW和BCM估计值无差异，它们可能可相互替代。但对于超重/肥胖的肾病患者则并非如此。
