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颈神经根病:流行病学、病因、诊断与治疗

Cervical radiculopathy: epidemiology, etiology, diagnosis, and treatment.

作者信息

Woods Barrett I, Hilibrand Alan S

机构信息

Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University, Philadelphia, PA.

出版信息

J Spinal Disord Tech. 2015 Jun;28(5):E251-9. doi: 10.1097/BSD.0000000000000284.

Abstract

Cervical radiculopathy is a relatively common neurological disorder resulting from nerve root dysfunction, which is often due to mechanical compression; however, inflammatory cytokines released from damaged intervertebral disks can also result in symptoms. Cervical radiculopathy can often be diagnosed with a thorough history and physical examination, but an magnetic resonance imaging or computed tomographic myelogram should be used to confirm the diagnosis. Because of the ubiquity of degenerative changes found on these imaging modalities, the patient's symptoms must correlate with pathology for a successful diagnosis. In the absence of myelopathy or significant muscle weakness all patients should be treated conservatively for at least 6 weeks. Conservative treatments consist of immobilization, anti-inflammatory medications, physical therapy, cervical traction, and epidural steroid injections. Cervical radiculopathy typically is self-limiting with 75%-90% of patients achieving symptomatic improvement with nonoperative care. For patients who are persistently symptomatic despite conservative treatment, or those who have a significant functional deficit surgical treatment is appropriate. Surgical options include anterior cervical decompression and fusion, cervical disk arthroplasty, and posterior foraminotomy. Patient selection is critical to optimize outcome.

摘要

神经根型颈椎病是一种相对常见的神经疾病,由神经根功能障碍引起,通常是由于机械性压迫所致;然而,受损椎间盘释放的炎性细胞因子也可导致症状出现。神经根型颈椎病通常可通过全面的病史采集和体格检查进行诊断,但应使用磁共振成像或计算机断层脊髓造影来确诊。由于在这些影像学检查中发现的退行性改变很普遍,患者的症状必须与病理结果相关才能成功诊断。在没有脊髓病或明显肌肉无力的情况下,所有患者都应接受至少6周的保守治疗。保守治疗包括固定、抗炎药物、物理治疗、颈椎牵引和硬膜外类固醇注射。神经根型颈椎病通常是自限性的,75% - 90%的患者通过非手术治疗症状会有所改善。对于尽管经过保守治疗仍持续有症状的患者,或有明显功能缺陷的患者,手术治疗是合适的。手术选择包括前路颈椎减压融合术、颈椎间盘置换术和后路椎间孔切开术。患者的选择对于优化治疗效果至关重要。

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