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艾滋病相关性胆管炎的放射学特征。

Radiological features of AIDS related cholangitis.

作者信息

McCarty M, Choudhri A H, Helbert M, Crofton M E

机构信息

Department of Radiology, St Mary's Hospital, London.

出版信息

Clin Radiol. 1989 Nov;40(6):582-5. doi: 10.1016/s0009-9260(89)80308-3.

DOI:10.1016/s0009-9260(89)80308-3
PMID:2598583
Abstract

Cryptosporidial infection is one of the recognised causes of diarrhoea in AIDS patients. It may also produce biliary tract disease. Fifteen out of 250 (6%) AIDS patients seen at our hospital had Cryptosporidial enteritis and five of the 15 (2% total) had clinical evidence of biliary tract disease. The radiological findings in these five patients are presented. Ultrasound examination of all five patients showed abnormalities in the biliary tree; five had dilatation and irregularity of the intra- and extrahepatic bile ducts with focal strictures, four had gall-bladder wall thickening, two had thickening of the common bile duct wall, two patients showed areas of increased reflectivity in the periductal regions of the liver and two had pancreatic duct dilatation. ERCP in one patient confirmed the ultrasound findings and Cryptosporidium oocytes were isolated from the collected bile. We conclude that Cryptosporidial infection in the biliary tree can produce distinctive appearances on ultrasound which may well obviate the need for more invasive investigations such as ERCP.

摘要

隐孢子虫感染是艾滋病患者腹泻的公认病因之一。它也可能引发胆道疾病。在我院就诊的250例艾滋病患者中,有15例(6%)患有隐孢子虫性肠炎,其中5例(占总数的2%)有胆道疾病的临床证据。现将这5例患者的影像学检查结果呈现如下。对所有5例患者进行超声检查均显示胆道树存在异常;5例肝内和肝外胆管有扩张、不规则及局灶性狭窄,4例胆囊壁增厚,2例胆总管壁增厚,2例患者肝脏胆管周围区域回声增强,2例胰管扩张。1例患者的内镜逆行胰胆管造影(ERCP)证实了超声检查结果,且从采集的胆汁中分离出了隐孢子虫卵囊。我们得出结论,胆道树中的隐孢子虫感染在超声检查中可呈现出独特表现,这很可能无需进行诸如ERCP等更具侵入性的检查。

相似文献

1
Radiological features of AIDS related cholangitis.艾滋病相关性胆管炎的放射学特征。
Clin Radiol. 1989 Nov;40(6):582-5. doi: 10.1016/s0009-9260(89)80308-3.
2
Sonographic diagnosis of cholangitis in AIDS patients.
Gastrointest Radiol. 1989 Spring;14(2):143-7. doi: 10.1007/BF01889179.
3
Cryptosporidiosis of the biliary tract in AIDS.
Radiology. 1991 Jul;180(1):51-6. doi: 10.1148/radiology.180.1.2052722.
4
Biliary tract obstruction in the acquired immunodeficiency syndrome.获得性免疫缺陷综合征中的胆道梗阻
Ann Intern Med. 1986 Aug;105(2):207-10. doi: 10.7326/0003-4819-105-2-207.
5
[Sclerosing cholangitis and AIDS].[硬化性胆管炎与艾滋病]
Rev Clin Esp. 1992 Feb;190(2):79-81.
6
Hepatobiliary cryptosporidiosis and cytomegalovirus infection mimicking metastatic cancer to the liver.模仿肝脏转移性癌的肝胆隐孢子虫病和巨细胞病毒感染。
Gastroenterology. 1991 Jun;100(6):1743-8. doi: 10.1016/0016-5085(91)90678-e.
7
Pathologic quiz case: a patient with acquired immunodeficiency syndrome and an unusual biliary infection.病理病例问答:一名患有获得性免疫缺陷综合征及罕见胆道感染的患者。
Arch Pathol Lab Med. 2003 Feb;127(2):243-4. doi: 10.5858/2003-127-243-PQ.
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Cryptosporidiosis in the acquired immunodeficiency syndrome: a study of 15 autopsy cases.获得性免疫缺陷综合征中的隐孢子虫病:15例尸检病例研究
Hum Pathol. 1991 Dec;22(12):1215-24. doi: 10.1016/0046-8177(91)90103-v.
9
Microsporidia infection in patients with the human immunodeficiency virus and unexplained cholangitis.人类免疫缺陷病毒感染且患有不明原因胆管炎患者的微孢子虫感染
N Engl J Med. 1993 Jan 14;328(2):95-9. doi: 10.1056/NEJM199301143280204.
10
AIDS-related cholangiopancreatographic changes.
Abdom Imaging. 1994 Sep-Oct;19(5):417-22. doi: 10.1007/BF00206928.

引用本文的文献

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The career of Maclyn McCarty.麦克林·麦卡蒂的职业生涯。
J Exp Med. 2005 Jun 6;201(11):1699-707. doi: 10.1084/jem.20050848.
2
Intestinal and extraintestinal cryptosporidiosis in AIDS patients.艾滋病患者的肠道及肠道外隐孢子虫病
Eur J Clin Microbiol Infect Dis. 1995 Aug;14(8):677-81. doi: 10.1007/BF01690873.
3
Biliary tract pathology in patients with AIDS.艾滋病患者的胆道病理
J Clin Pathol. 1993 Aug;46(8):691-3. doi: 10.1136/jcp.46.8.691.
4
AIDS-related cholangiopathy. Critical analysis of a prospective series of 26 patients.艾滋病相关胆管病。对26例患者前瞻性系列研究的批判性分析。
Dig Dis Sci. 1993 Jun;38(6):1113-8. doi: 10.1007/BF01295729.