Seki Yosuke, Kasama Kazunori, Hashimoto Kenkichi
Weight Loss and Metabolic Surgery Center, Yotsuya Medical Cube, 7-7 Nibancho, Chiyoda-ku, Tokyo, 102-0084, Japan.
Obes Surg. 2016 Jan;26(1):138-45. doi: 10.1007/s11695-015-1728-1.
Recently, laparoscopic sleeve gastrectomy (LSG) as a standalone bariatric procedure has rapidly gained popularity worldwide mainly because of its technical simplicity and the relatively good short-term outcome. In Japan, according to a domestic survey, 71 % of the bariatric procedures performed were LSG. However, the number of studies reporting long-term results are still not enough; particularly, data for Asian patients are scarce.
The objective of this study was to evaluate the long-term outcomes for LSG in morbidly obese Japanese regarding weight loss and safety.
Between October 2005 and July 2013, 179 morbidly obese Japanese patients (Female 89/Male 90) underwent LSG as a standalone procedure. The mean age was 40.7 years (range, 20-72 years), and the mean preoperative body weight and body mass index (BMI) were 120.4 kg (range, 71.4-231.6 kg) and 43.3 kg/m(2) (range, 30.9-76.5 kg/m(2)), respectively. All patients were evaluated and managed under a strict multidisciplinary team approach.
The mean BMI declined to 30.0 ± 8.7 kg/m(2) at 1 year, 29.1 ± 8.6 kg/m(2) at 2 years, 28.8 ± 8.7 kg/m(2) at 3 years, 29.3 ± 9.2 kg/m(2) at 4 years, and 32.7 ± 13.6 kg/m(2) at 5 years or more (p < 0.001). The mean percent total body weight loss (%TWL) achieved was 32.4 ± 12.9 % at 1 year, 34.3 ± 12.9 % at 2 years, 34.4 ± 11.6 % at 3 years, 32.8 ± 10.9 % at 4 years, and 29.5 ± 11.8 % at 5 years or more. Super morbidly obese patients and patients whose gastric tube was created using a thicker (45 Fr.) bougie had a tendency to achieve less weight loss. Early and late complications occurred in 16 patients (8.9 %) and in seven patients (3.9 %), respectively. Revision surgeries were required in six patients (3.4 %). The reasons for revision surgery were insufficient weight loss in five patients and intractable gastroesophageal reflux disease (GERD) in one patient.
LSG for Japanese morbidly obese patients is safe, effective, and acceptably durable up to 5 years although some complications unique to the procedure such as leakage from the staple line and intractable GERD occur. For super morbidly obese patients, other surgical options may be required.
近年来,腹腔镜袖状胃切除术(LSG)作为一种独立的减肥手术在全球范围内迅速普及,这主要归因于其技术操作简单以及相对良好的短期效果。在日本,根据一项国内调查,71%的减肥手术为LSG。然而,报道长期结果的研究数量仍然不足;尤其是亚洲患者的数据稀缺。
本研究旨在评估病态肥胖的日本患者接受LSG后的长期体重减轻和安全性结果。
2005年10月至2013年7月期间,179例病态肥胖的日本患者(女性89例/男性90例)接受了作为独立手术的LSG。平均年龄为40.7岁(范围20 - 72岁),术前平均体重和体重指数(BMI)分别为120.4 kg(范围71.4 - 231.6 kg)和43.3 kg/m²(范围30.9 - 76.5 kg/m²)。所有患者均在严格的多学科团队方法下进行评估和管理。
1年时平均BMI降至30.0±8.7 kg/m²,2年时为29.1±8.6 kg/m²,3年时为28.8±8.7 kg/m²,4年时为29.3±9.2 kg/m²,5年及以上时为32.7±13.6 kg/m²(p < 0.001)。1年时实现的平均总体重减轻百分比(%TWL)为32.4±12.9%,2年时为34.3±12.9%,3年时为34.4±11.6%,4年时为32.8±10.9%,5年及以上时为29.5±11.8%。超级病态肥胖患者以及使用较粗(45 Fr.)探条制作胃管的患者减重趋势较小。早期和晚期并发症分别发生在16例患者(8.9%)和7例患者(3.9%)中。6例患者(3.4%)需要进行修正手术。修正手术的原因是5例患者体重减轻不足,1例患者患有难治性胃食管反流病(GERD)。
对于日本病态肥胖患者,LSG在5年内是安全、有效的,且耐久性可接受,尽管该手术存在一些独特的并发症,如吻合口漏和难治性GERD。对于超级病态肥胖患者,可能需要其他手术选择。