基因组学时代药物研发中的产学研合作。
Academic-industrial partnerships in drug discovery in the age of genomics.
机构信息
Biogen, 225 Binney Street, Cambridge, MA 02142, USA.
Biogen, 225 Binney Street, Cambridge, MA 02142, USA.
出版信息
Trends Biotechnol. 2015 Jun;33(6):320-2. doi: 10.1016/j.tibtech.2015.02.009.
Many US FDA-approved drugs have been developed through productive interactions between the biotechnology industry and academia. Technological breakthroughs in genomics, in particular large-scale sequencing of human genomes, is creating new opportunities to understand the biology of disease and to identify high-value targets relevant to a broad range of disorders. However, the scale of the work required to appropriately analyze large genomic and clinical data sets is challenging industry to develop a broader view of what areas of work constitute precompetitive research.
许多获得美国食品和药物管理局批准的药物都是通过生物技术行业和学术界之间富有成效的互动开发出来的。基因组学，特别是人类基因组的大规模测序方面的技术突破，正在为理解疾病的生物学和确定与广泛的疾病相关的高价值靶点创造新的机会。然而，为了适当地分析大型基因组和临床数据集，需要进行规模庞大的工作，这促使行业对哪些工作领域构成竞争前研究有了更广泛的认识。
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