Matsuura Mizue, Inamori Masahiko, Nakajima Atsushi, Komiya Yasuhiko, Inoh Yumi, Kawasima Keigo, Naitoh Mai, Fujita Yuji, Eduka Akiko, Kanazawa Noriyoshi, Uchiyama Shiori, Tani Rie, Kawana Kennichi, Ohtani Setsuya, Nagase Hajime
Mizue Matsuura, Masahiko Inamori, Atsushi Nakajima, Hepatology and Gastroenterology, Yokohama City University Hospital, Yokohama 236-0004, Japan.
World J Gastroenterol. 2015 May 14;21(18):5555-9. doi: 10.3748/wjg.v21.i18.5555.
To evaluate the effectiveness of barium impaction therapy for patients with colonic diverticular bleeding.
We reviewed the clinical charts of patients in whom therapeutic barium enema was performed for the control of diverticular bleeding between August 2010 and March 2012 at Yokohama Rosai Hospital. Twenty patients were included in the review, consisting of 14 men and 6 women. The median age of the patients was 73.5 years. The duration of the follow-up period ranged from 1 to 19 mo (median: 9.8 mo). Among the 20 patients were 11 patients who required the procedure for re-bleeding during hospitalization, 6 patients who required it for re-bleeding that developed after the patient left the hospital, and 3 patients who required the procedure for the prevention of re-bleeding. Barium (concentration: 150 w%/v%) was administered per the rectum, and the leading edge of the contrast medium was followed up to the cecum by fluoroscopy. After confirmation that the ascending colon and cecum were filled with barium, the enema tube was withdrawn, and the patient's position was changed every 20 min for 3 h.
Twelve patients remained free of re-bleeding during the follow-up period (range: 1-19 mo) after the therapeutic barium enema, including 9 men and 3 women with a median age of 72.0 years. Re-bleeding occurred in 8 patients including 5 men and 3 women with a median age of 68.5 years: 4 developed early re-bleeding, defined as re-bleeding that occurs within one week after the procedure, and the remaining 4 developed late re-bleeding. The DFI (disease-free interval) decreased 0.4 for 12 mo. Only one patient developed a complication from therapeutic barium enema (colonic perforation).
Therapeutic barium enema is effective for the control of diverticular hemorrhage in cases where the active bleeding site cannot be identified by colonoscopy.
评估钡剂灌肠疗法对结肠憩室出血患者的疗效。
我们回顾了2010年8月至2012年3月在横滨罗萨医院接受治疗性钡剂灌肠以控制憩室出血的患者的临床病历。该回顾纳入了20例患者,其中男性14例,女性6例。患者的中位年龄为73.5岁。随访期为1至19个月(中位值:9.8个月)。20例患者中,11例因住院期间再次出血需要进行该操作,6例因出院后发生再次出血需要进行该操作,3例因预防再次出血需要进行该操作。经直肠给予钡剂(浓度:150 w%/v%),通过荧光透视追踪造影剂的前缘直至盲肠。确认升结肠和盲肠充满钡剂后,拔出灌肠管,患者每20分钟变换一次体位,持续3小时。
12例患者在治疗性钡剂灌肠后的随访期(1至19个月)内未再次出血,其中包括9例男性和3例女性,中位年龄为72.0岁。8例患者再次出血,其中包括5例男性和3例女性,中位年龄为68.5岁:4例发生早期再次出血,定义为操作后一周内发生的再次出血,其余4例发生晚期再次出血。12个月时无病生存期(DFI)降低了0.4。仅一名患者因治疗性钡剂灌肠出现并发症(结肠穿孔)。
对于结肠镜检查无法确定活动性出血部位的病例,治疗性钡剂灌肠对控制憩室出血有效。