Lewis Myron
Memphis Gastroenterology Group, Germantown, TN 38138, USA.
J Clin Gastroenterol. 2008 Nov-Dec;42(10):1156-8. doi: 10.1097/MCG.0b013e3181862ad1.
Diverticula of the large intestine constitute a common source of lower gastrointestinal (GI) bleeding both occult and massive and are a particular common cause of right-sided colonic hemorrhage. Bleeding in all cases is due to rupture of the underlying vasa rectum. In all cases, rupture of the artery is not circumferential, but eccentric having occurred toward the lumen of the diverticula. It is rare to see either acute or chronic diverticulitis associated with this situation. Lower GI bleeding is frequent in the elderly secondary to diverticular disease and occurs in about 10% to 30% GI bleeds and actually is much less frequent than upper GI bleeding. Diverticular disease actually is uncommon in people under the age of 40. However, by the age of 50 almost one-third of the population has diverticulosis. Ninety percent of the diverticula are in the left colon, but bleeding is from the right colon at least 50% of the time. Diverticular hemorrhage will cease spontaneously in about 90% cases. Most often, there is no inflammatory process around the diverticular bleeding. Hypertension even may be a predisposing factor. Also anticoagulation, diabetes mellitus, and ischemic heart disease are associated with diverticular hemorrhage. As far as treatment is concerned, conservative therapy is usually the best approach. One would like to avoid angiography and surgery if at all possible. There is a significant recurrence of bleeding in those patients who are treated even with angiography and with surgery. Etiology of the bleeding is not really well understood and the diagnosis and treatment is quite difficult in some situations.
大肠憩室是下消化道(GI)隐匿性和大量出血的常见来源,是右侧结肠出血的特别常见原因。所有病例的出血均由于其下方的直血管破裂所致。在所有病例中,动脉破裂并非呈环形,而是偏心性地朝向憩室腔发生。很少见到急性或慢性憩室炎与此情况相关。由于憩室病,老年人下消化道出血很常见,约占胃肠道出血的10%至30%,实际上比上消化道出血的频率要低得多。憩室病在40岁以下的人群中实际上并不常见。然而,到50岁时,几乎三分之一的人口患有憩室病。90%的憩室位于左半结肠,但至少50%的出血来自右半结肠。憩室出血约90%的病例会自发停止。大多数情况下,憩室出血周围没有炎症过程。高血压甚至可能是一个诱发因素。此外,抗凝治疗、糖尿病和缺血性心脏病与憩室出血有关。就治疗而言,保守治疗通常是最佳方法。如果可能,应尽量避免血管造影和手术。即使接受血管造影和手术治疗的患者,出血也有显著的复发率。出血的病因尚未完全明确,在某些情况下,诊断和治疗相当困难。