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脑静脉窦血栓形成中的多发性颅神经病变

Multiple cranial neuropathies in cerebral venous sinus thrombosis.

作者信息

Mubbashir Shariff Erum, Alhameed Majed

机构信息

KSA, Neurosciences , King Fahad Medical City , Riyadh 11525 , Saudi Arabia.

出版信息

Oxf Med Case Reports. 2014 May 7;2014(2):21-3. doi: 10.1093/omcr/omu007. eCollection 2014 May.

Abstract

Clinical presentation of cerebral venous sinus thrombosis (CVST) is varied and often mimics many neurological disorders, making it a diagnostic challenge, and cranial nerve palsy in CVST is rare and its pathophysiology remains unclear. We report a case of a 19-year-old male with a history of whiplash injury, admitted with extensive CVST, developed right facial nerve palsy with extension of thrombus into the ipsilateral transverse sinus, sigmoid sinus and internal jugular vein. Later, he developed left facial nerve palsy with partial left occulomotor weakness. We suggest that either reversible compromised oxygen or glucose consumption within the intrinsic vascular system of the nerve, resulting in cranial nerve abnormalities. CVST should be considered in cases of trivial trauma, even in the absence of hyper-coagulable states, and it can have atypical presentation like multiple cranial neuropathies.

摘要

脑静脉窦血栓形成(CVST)的临床表现多样,常与许多神经系统疾病相似,这使其成为一项诊断挑战,而且CVST中的颅神经麻痹罕见,其病理生理学仍不清楚。我们报告一例19岁男性,有挥鞭样损伤史,因广泛CVST入院,随着血栓延伸至同侧横窦、乙状窦和颈内静脉而出现右侧面神经麻痹。后来,他又出现左侧面神经麻痹并伴有部分左侧动眼神经功能减弱。我们认为,要么是神经内在血管系统内氧或葡萄糖消耗可逆性受损,从而导致颅神经异常。即使在没有高凝状态的情况下,对于轻微创伤病例也应考虑CVST,它可能有像多发性颅神经病变这样的非典型表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc9a/4369979/481c721d5faf/omu00701.jpg

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