Luo Yaxi, Tian Xin, Wang Xuefeng
Chongqing Key Laboratory of Neurology, Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Center of Epilepsy, Beijing Institute for Brain Disorders, Beijing, China.
Front Aging Neurosci. 2018 Jan 30;10:2. doi: 10.3389/fnagi.2018.00002. eCollection 2018.
Cerebral venous thrombosis (CVT), also called cerebral venous sinus thrombosis (CVST), is a cerebrovascular disease with diverse clinical manifestations that often affects young adults, women of childbearing age, and children. It's most common clinical manifestations are headache, seizures, altered consciousness, and neurological focal signs on physical examination. CVT can manifest as a single symptom, or it can present as a syndrome consisting of multiple symptoms. This non-specific clinical picture makes diagnosing CVT difficult. Although the mortality rate of CVT has been significantly reduced by improvements in treatment and diagnostic techniques, the mortality rate of severe CVT remains as high as 34.2%. Survivors of this type of CVT have varying degrees of residual symptoms and are not able to return to their previous work. Hence, we performed a comprehensive literature search in the PubMed, EMBASE, and Medline databases to review the diagnosis and treatment of CVT.
脑静脉血栓形成（CVT），也称为脑静脉窦血栓形成（CVST），是一种临床表现多样的脑血管疾病，常影响年轻人、育龄妇女和儿童。其最常见的临床表现为头痛、癫痫发作、意识改变以及体格检查时的神经局灶体征。CVT可表现为单一症状，也可表现为由多种症状组成的综合征。这种非特异性的临床表现使得CVT的诊断较为困难。尽管治疗和诊断技术的进步已使CVT的死亡率显著降低，但重症CVT的死亡率仍高达34.2%。这类CVT的幸存者有不同程度的残留症状，无法恢复到以前的工作状态。因此，我们在PubMed、EMBASE和Medline数据库中进行了全面的文献检索，以综述CVT的诊断和治疗。
