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以急性肝衰竭为表现的原发性肝结核

Primary hepatic tuberculosis presenting as acute liver failure.

作者信息

Jain Deepak, Aggarwal H K, Jain Promil, Pawar Sunil

机构信息

Department of Medicine , Pt. B.D. Sharma University of Health Sciences , Rohtak, Haryana , India.

Department of Pathology , Pt. B.D. Sharma University of Health Sciences , Rohtak, Haryana , India.

出版信息

Oxf Med Case Reports. 2014 Dec 23;2014(9):153-5. doi: 10.1093/omcr/omu058. eCollection 2014 Dec.

DOI:10.1093/omcr/omu058
PMID:25988063
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4370019/
Abstract

Abdominal tuberculosis is a common clinical entity in Indian subcontinent; however, hepatic tuberculosis in the absence of miliary abdominal tuberculosis is restricted to the case reports and small case series in English literature. It mimics common liver diseases like liver abscess and tumors. We report a case of 25-year-old immunocompetent female who presented with features of acute liver failure. Ultrasonography (USG) abdomen revealed multiple hypoechoic lesions. However, patient expired within 48 h of presentation but her liver autopsy revealed multiple epithelioid cell caseating granulomas with positive staining for acid fast bacilli (AFB). Polymerase chain reaction (PCR) was also positive for Mycobacterium tuberculosis.

摘要

腹部结核在印度次大陆是一种常见的临床病症;然而,在无粟粒性腹部结核的情况下,肝结核在英文文献中仅限于病例报告和小病例系列。它酷似肝脓肿和肿瘤等常见肝脏疾病。我们报告一例25岁免疫功能正常的女性,她表现出急性肝衰竭的症状。腹部超声检查发现多个低回声病变。然而,患者在就诊后48小时内死亡,但她的肝脏尸检显示有多个上皮样细胞干酪样肉芽肿,抗酸杆菌(AFB)染色呈阳性。聚合酶链反应(PCR)检测结核分枝杆菌也呈阳性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/665a/4370019/505c6dbf4f2e/omu05801.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/665a/4370019/505c6dbf4f2e/omu05801.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/665a/4370019/505c6dbf4f2e/omu05801.jpg

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Isolated hepatic tuberculosis: An uncommon presentation of a common culprit.孤立性肝结核:常见病因的罕见表现。
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