Nikas Dimitrios C, Post Alexander F, Choudhri Asim F, Mazzola Catherine A, Mitchell Laura, Flannery Ann Marie
Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois
2Advocate Children's Hospital, Oak Lawn, Illinois;
J Neurosurg Pediatr. 2014 Nov;14 Suppl 1:77-81. doi: 10.3171/2014.7.PEDS14330.
The objective of this systematic review is to answer the following question: Does ventricle size after treatment have a predictive value in determining the effectiveness of surgical intervention in pediatric hydrocephalus?
The US National Library of Medicine PubMed/MEDLINE database and the Cochrane Database of Systematic Reviews were searched using MeSH headings and key words relevant to change in ventricle size after surgical intervention for hydrocephalus in children. An evidentiary table was assembled summarizing the studies and the quality of evidence (Classes I-III).
Six articles satisfied inclusion criteria for the evidentiary tables for this part of the guidelines. All were Class III retrospective studies. CONCLUSIONS/RECOMMENDATIon: There is insufficient evidence to recommend a specific change in ventricle size as a measurement of the effective treatment of hydrocephalus and as a measurement of the timing and effectiveness of treatments including ventriculoperitoneal shunts and third ventriculostomies.
Level III, unclear clinical certainty.
本系统评价的目的是回答以下问题：治疗后脑室大小在确定小儿脑积水手术干预效果方面是否具有预测价值？
使用与小儿脑积水手术干预后脑室大小变化相关的医学主题词和关键词，检索美国国立医学图书馆的PubMed/MEDLINE数据库以及Cochrane系统评价数据库。汇总了一份证据表，总结了各项研究及证据质量（I - III级）。
有6篇文章符合本部分指南证据表的纳入标准。所有文章均为III级回顾性研究。
结论/建议：没有足够的证据推荐将特定的脑室大小变化作为衡量脑积水有效治疗的指标，以及作为衡量包括脑室腹腔分流术和第三脑室造瘘术等治疗的时机和效果的指标。
III级，临床确定性不明确。
