Andreasen F M, Andreasen J O, Bayer T
Endod Dent Traumatol. 1989 Feb;5(1):11-22. doi: 10.1111/j.1600-9657.1989.tb00331.x.
A population of 85 patients, comprising 95 root-fractured permanent incisors followed up to 11 years, was studied prospectively for the type of fracture healing that occurred (i.e. union of the fragments by interposition of hard tissue (HT) or connective tissue (CT), or nonunion characterized by interposition of granulation tissue between the fragments (GT)). Initial treatment was provided according to established treatment guidelines by the attending oral surgeon at the emergency room. Follow-up examination and treatment were provided by 2 of the authors. It appeared that GT could be diagnosed after approximately 3 weeks, while HT or CT could be diagnosed approximately 6 weeks after trauma. Many factors considered one at a time were found to have a significant or nearly significant effect on the type of fracture healing that occurred. However, a multivariate regression analysis revealed that the following factors were significantly related to fracture healing by HT: a large diameter of the apical foramen and severity of luxation of the coronal fragment (concussion/subluxation greater than lateral luxation greater than extrusion); fracture healing by CT: the presence of restorations in the injured teeth at the time of injury and the presence of marginal periodontal disease; and fracture nonhealing by GT: type of fixation (i.e. orthodontic band fixation versus acid etch or no fixation), antibiotic therapy, a constricted apical foramen, increased loosening of the coronal fragment, and stage of root development (GT never occurred in teeth with open apices). It was previously demonstrated following luxation injuries that type of luxation, stage of root development and type of fixation (orthodontic bands versus acid etch or no fixation) determined the prognosis of pulp survival. It therefore appears that the general factors that are able to predict the type of healing seen after root fracture are the same as those after luxation injuries, supporting the hypothesis that root fractures are another form of luxation injury, this time of only the coronal fragment.
对85例患者的95颗根折恒牙进行了为期11年的前瞻性研究,观察骨折愈合的类型(即通过硬组织(HT)或结缔组织(CT)插入使骨折碎片愈合,或骨折不愈合,其特征为骨折碎片间有肉芽组织(GT)插入)。急诊室的主治口腔外科医生根据既定的治疗指南进行初始治疗。随访检查和治疗由两位作者提供。结果显示,大约3周后可诊断出GT,而HT或CT可在创伤后约6周诊断出来。逐一考虑的许多因素被发现对发生的骨折愈合类型有显著或近乎显著的影响。然而,多变量回归分析显示,以下因素与HT导致的骨折愈合显著相关:根尖孔直径大以及冠部骨折片的脱位严重程度(震荡/半脱位大于侧方脱位大于脱出);CT导致的骨折愈合:受伤时患牙有修复体以及存在边缘性牙周病;GT导致的骨折不愈合:固定类型(即正畸带环固定与酸蚀或无固定)、抗生素治疗、根尖孔狭窄、冠部骨折片松动增加以及牙根发育阶段(根尖开放的牙齿从未发生GT)。先前的研究表明,在脱位损伤后,脱位类型、牙根发育阶段和固定类型(正畸带环与酸蚀或无固定)决定了牙髓存活的预后。因此,似乎能够预测根折后愈合类型的一般因素与脱位损伤后的因素相同,这支持了根折是脱位损伤的另一种形式的假设,这次只是冠部骨折片的脱位损伤。