铑（III）催化偶氮苯与α-重氮酯的直接偶联反应：简便合成噌啉-3（2H）-酮
Rh(III)-Catalyzed Direct Coupling of Azobenzenes with α-Diazo Esters: Facile Synthesis of Cinnolin-3(2H)-ones.
作者信息
Sharma Satyasheel, Han Sang Hoon, Han Sangil, Ji Wontae, Oh Jongchan, Lee Seok-Yong, Oh Joa Sub, Jung Young Hoon, Kim In Su
机构信息
†School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.
‡College of Pharmacy, Dankook University, Cheonan 330-714, Republic of Korea.
出版信息
Org Lett. 2015 Jun 5;17(11):2852-5. doi: 10.1021/acs.orglett.5b01298. Epub 2015 May 20.
The rhodium(III)-catalyzed direct C-H functionalization of azobenzenes with α-diazo compounds is described. These transformations provide the facile and efficient construction of C2-alkylated azobenzenes or highly substituted cinnolin-3(2H)-ones. Furthermore, this protocol leads to the formation of cinnolin-3(2H)-ones using a diazo derivative of Meldrum's acid.
描述了铑（III）催化偶氮苯与α-重氮化合物的直接C-H官能化反应。这些转化反应能够简便高效地构建C2-烷基化偶氮苯或高度取代的噌啉-3（2H）-酮。此外，该方法使用丙二酸亚异丙酯的重氮衍生物可生成噌啉-3（2H）-酮。
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