Legon'kova L F, Lukienko P I, Bushma M I
Farmakol Toksikol. 1989 Sep-Oct;52(5):47-50.
Administration to intact male rats of folic acid (25 mg/kg intragastrically for 14 days) was shown to increase and that of methotrexate (0.5 mg/kg subcutaneously) for 14 days) to decrease the activities of the rat liver uridine-diphosphate-glucuronosyl- and glutathione-S-transferases.
给完整雄性大鼠灌胃叶酸（25毫克/千克，持续14天）显示可增加其肝脏尿苷二磷酸葡萄糖醛酸基转移酶和谷胱甘肽-S-转移酶的活性，而皮下注射甲氨蝶呤（0.5毫克/千克，持续14天）则会降低这些酶的活性。
