Belousov Iu B, Abazova F I, Kholodov L E, Chervinskaia T A, Sokolov A V
Farmakol Toksikol. 1989 Sep-Oct;52(5):63-8.
Pharmacokinetics of theopek--a new original slow release formulation of theophylline--as compared with theotard and theodur was studied in patients with bronchial asthma. The pharmacokinetic parameters of this product were shown to be comparable. A significant correlation between blood theophylline concentration and the bronchodilating and diuretic effects in patients with bronchial asthma was revealed.
在支气管哮喘患者中研究了茶喘平(一种新的茶碱缓释制剂)与茶喘宁和氨茶碱相比的药代动力学。结果显示该产品的药代动力学参数具有可比性。研究还揭示了支气管哮喘患者血中茶碱浓度与支气管扩张和利尿作用之间存在显著相关性。