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Ann Transl Med. 2015 Apr;3(6):77. doi: 10.3978/j.issn.2305-5839.2015.01.25.
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J Oral Maxillofac Surg. 2009 Jan;67(1):125-33. doi: 10.1016/j.joms.2008.08.015.

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Tranexamic Acid as a Preventive Strategy Against Periprosthetic Joint Infection in Aseptic Revision Arthroplasty: A Comprehensive Review.氨甲环酸作为无菌性翻修关节置换术中假体周围感染的预防策略：一项综述
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Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic and long bone fractures.用于预防接受确定性固定或关节置换术的髋部、骨盆和长骨骨折患者出血的药物干预措施。
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Comparison of blood loss between intra-articular and intra-venous administration of tranexamic acid in primary total knee arthroplasty.原发性全膝关节置换术中关节内与静脉内注射氨甲环酸的失血比较。
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Tranexamic acid is associated with selective increase in inflammatory markers following total knee arthroplasty (TKA): a pilot study.氨甲环酸与全膝关节置换术（TKA）后炎症标志物的选择性升高有关：一项初步研究。
J Orthop Surg Res. 2018 Jun 18;13(1):149. doi: 10.1186/s13018-018-0855-5.
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A prospective, randomized, comparative study of intravenous alone and combined intravenous and intraarticular administration of tranexamic acid in primary total knee replacement.氨甲环酸单独静脉注射与静脉联合关节内注射在初次全膝关节置换术中的前瞻性、随机、对照研究。
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Efficacy of tranexamic acid in reducing blood loss and blood transfusion in idiopathic scoliosis: a systematic review and meta-analysis.氨甲环酸在减少特发性脊柱侧凸术中失血及输血方面的疗效：一项系统评价与荟萃分析
J Spine Surg. 2017 Dec;3(4):531-540. doi: 10.21037/jss.2017.08.17.
10
The Use of Tranexamic Acid in Rhytidectomy Patients.氨甲环酸在除皱手术患者中的应用。
Plast Reconstr Surg Glob Open. 2016 May 25;4(5):e716. doi: 10.1097/GOX.0000000000000745. eCollection 2016 May.

本文引用的文献

1
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement: a double-blind, randomized, controlled, noninferiority clinical trial.关节内局部应用与静脉应用氨甲环酸减少初次全膝关节置换术中失血的比较：一项双盲、随机、对照、非劣效性临床试验。
J Bone Joint Surg Am. 2014 Dec 3;96(23):1937-44. doi: 10.2106/JBJS.N.00060.
2
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety.氨甲环酸在美国全髋关节或膝关节置换术患者中的应用及术后结局：有效性和安全性的回顾性分析
BMJ. 2014 Aug 12;349:g4829. doi: 10.1136/bmj.g4829.
3
Impact of the economic downturn on total joint replacement demand in the United States: updated projections to 2021.美国经济衰退对全关节置换需求的影响：更新至 2021 年的预测。
J Bone Joint Surg Am. 2014 Apr 16;96(8):624-30. doi: 10.2106/JBJS.M.00285.
4
Reduced blood loss after intra-articular tranexamic acid injection during total knee arthroplasty: a meta-analysis of the literature.关节内注射氨甲环酸减少全膝关节置换术后失血：文献荟萃分析。
Knee Surg Sports Traumatol Arthrosc. 2014 Dec;22(12):3181-90. doi: 10.1007/s00167-013-2814-3. Epub 2013 Dec 19.
5
Blood transfusion after primary total knee arthroplasty can be significantly minimised through a multimodal blood-loss prevention approach.初次全膝关节置换术后输血可以通过多模式失血预防方法显著减少。
Int Orthop. 2014 Feb;38(2):347-54. doi: 10.1007/s00264-013-2188-7. Epub 2013 Dec 7.
6
The use of tranexamic acid to reduce blood loss and transfusion in major orthopedic surgery: a meta-analysis.氨甲环酸在大型骨科手术中减少失血和输血的应用：荟萃分析。
J Surg Res. 2014 Jan;186(1):318-27. doi: 10.1016/j.jss.2013.08.020. Epub 2013 Sep 13.
7
Scientific letter: could tranexamic acid use in surgery reduce perioperative myocardial infarction?科学信函：手术中使用氨甲环酸能否降低围手术期心肌梗死的发生率？
Heart. 2013 Dec;99(23):1785. doi: 10.1136/heartjnl-2013-304292. Epub 2013 Jun 7.
8
Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis.氨甲环酸与全膝关节和髋关节置换术中失血的减少：一项荟萃分析。
BMC Res Notes. 2013 May 7;6:184. doi: 10.1186/1756-0500-6-184.
9
A systematic review of the effect of red blood cell transfusion on mortality: evidence from large-scale observational studies published between 2006 and 2010.一项关于红细胞输血对死亡率影响的系统评价：来自 2006 年至 2010 年间发表的大规模观察性研究的证据。
BMJ Open. 2013 May 2;3(5):e002154. doi: 10.1136/bmjopen-2012-002154.
10
Do we really need tranexamic acid in total hip arthroplasty? A meta-analysis of nineteen randomized controlled trials.全髋关节置换术中是否真的需要使用氨甲环酸？一项十九项随机对照试验的荟萃分析。
Arch Orthop Trauma Surg. 2013 Jul;133(7):1017-27. doi: 10.1007/s00402-013-1761-2. Epub 2013 Apr 25.

Tranexamic acid and orthopedic surgery-the search for the holy grail of blood conservation.

作者信息

Danninger Thomas, Memtsoudis Stavros G

机构信息

1 Department of Anesthesiology, Perioperative Medicine and Critical Care Medicine, Paracelsus Medical University, Muellner Hauptstrasse 48, 5020 Salzburg, Austria ; 2 Department of Anesthesiology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY 10021, USA.

出版信息

Ann Transl Med. 2015 Apr;3(6):77. doi: 10.3978/j.issn.2305-5839.2015.01.25.

DOI:10.3978/j.issn.2305-5839.2015.01.25
PMID:25992376
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4416949/
Abstract
摘要