Knösel Michael, Fendel Christine, Jung Klaus, Sandoval Paulo, Engelke Wilfried G
a Professor, Department of Orthodontics, University Medical Center Göttingen, Göttingen, Germany.
b Research Fellow and Medical Student, University Medical Center Giessen & Marburg, Giessen, Germany.
Angle Orthod. 2016 Mar;86(2):315-23. doi: 10.2319/021215-98.1. Epub 2015 May 20.
To test the null hypothesis of no significant difference between intraoral pressure characteristics in infants with cleft lip and palate (CLP) with or without presurgical orthopedic (PSO) plates (groups CLP and CLP-PSO), compared with noncleft infants.
Intraoral atmospheric pressure assessments were performed on 17 subjects with preoperative CLP (m/f, 11/6; mean/SD, 4.76/0.92 months) and a matched control group (n = 24; m/f, 15/9; mean/SD, 4.88/0.9 months), for 200 seconds, simultaneously at the vestibulum (vestibular space [VS]) and at the palate (subpalatal space [SPS]), using a prepared pacifier connected to a digital manometer. Areas under the pressure curves (AUC), frequencies, durations, and magnitudes of swallowing peaks and pressure resting plateaus were compared between trial groups and locations (VS, SPS) using a two-factor analysis of variance for repeated measures, Kruskal-Wallis test, and Mann-Whitney U-test (α = .05).
The null hypothesis was rejected: Globally, there were statistically significant differences in intraoral pressure characteristics between groups CLP, CLP-PSO, and control (all P < .01), with significantly higher negative pressures (AUC) in the control subjects compared with those of CLP or CLP-PSO. There were significant effects by the location of pressure recordings (VS, SPS) and their interaction with all treatment groups. Differences between noncleft and CLP subjects were more pronounced in the VS than in the SPS. There was no significant effect by PSO.
PSO does not improve deviated swallowing characteristics during suction in CLP infants.
检验唇腭裂(CLP)婴儿在使用或不使用术前矫形(PSO)板(CLP组和CLP - PSO组)时口腔内压力特征与非腭裂婴儿之间无显著差异的零假设。
对17名术前唇腭裂患者(男/女,11/6;平均/标准差,4.76/0.92个月)和一个匹配的对照组(n = 24;男/女,15/9;平均/标准差,4.88/0.9个月)进行口腔内大气压评估,持续200秒,同时在前庭(前庭间隙[VS])和腭部(腭下间隙[SPS])使用连接数字压力计的特制奶嘴进行测量。使用重复测量的双因素方差分析、Kruskal - Wallis检验和Mann - Whitney U检验(α = 0.05)比较试验组和测量部位(VS、SPS)之间压力曲线下面积(AUC)、频率、持续时间以及吞咽峰值和压力平稳平台的幅度。
零假设被拒绝:总体而言,CLP组、CLP - PSO组和对照组之间口腔内压力特征存在统计学显著差异(所有P < 0.01),与CLP组或CLP - PSO组相比,对照组受试者的负压(AUC)显著更高。压力记录部位(VS、SPS)及其与所有治疗组的相互作用有显著影响。非腭裂和CLP受试者之间的差异在前庭比在腭下间隙更明显。PSO没有显著影响。
PSO不能改善CLP婴儿吸吮时异常的吞咽特征。