Wang Zhenyu, Xue Qing, Xiong Xiuchun, Li Peiyang, Tian Chunyang, Fu Cehong, Wang Yuping, Yao Dezhong, Xu Peng
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2015 Feb;32(1):8-12.
Studies have shown that the clinical manifestation of patients with neuropsychiatric disorders might be related to the abnormal connectivity of brain functions. Psychogenic non-epileptic seizures (PNES) are different from the conventional epileptic seizures due to the lack of the expected electroencephalographically epileptic changes in central nervous system, but are related to the presence of significant psychological factors. Diagnosis of PNES remains challenging. We found in the present work that the connectivity between the frontal and parieto-occipital in PNES was weaker than that of the controls by using network analysis based on electroencephalogram (EEG) signals. In addition, PNES were recognized by using the network properties as linear discriminant nalysis (LDA) input and classification accuracy was 85%. This study may provide a feasible tool for clinical diagnosis of PNES.
研究表明,神经精神疾病患者的临床表现可能与脑功能连接异常有关。心因性非癫痫性发作(PNES)与传统癫痫发作不同,因为中枢神经系统缺乏预期的脑电图癫痫变化,但与显著心理因素的存在有关。PNES的诊断仍然具有挑战性。我们在本研究中发现,通过基于脑电图(EEG)信号的网络分析,PNES患者额叶与顶枕叶之间的连接比对照组弱。此外,以网络属性作为线性判别分析(LDA)输入来识别PNES,分类准确率为85%。本研究可能为PNES的临床诊断提供一种可行的工具。