Wan Hongli, Feng Erkai, Wu Hongchao, Yang Yanling, Ni Jia, Chen Lizhi
Bing Du Xue Bao. 2015 Jan;31(1):85-90.
Mink plasmacytosis, caused by Aleutian Mink Disease Virus (AMDV), poses a threat to the development of the animal fur industry. Neutralizing antibodies against AMDV may result in a persistent infection rather than providing protection for minks. To date,no specific methods to prevent or cure this disease have been developed. In order to eliminate mink plasmacytosis, antibody detection technology has been used globally as a dominant approach to screen for AMDV-positive minks. This paper introduces the classical technology, counterimmunoelectrophoresis and emerging technology in terms of AMDV antibody detection,and provides a glimpse into the future development of these technologies.
由阿留申水貂病病毒（AMDV）引起的水貂浆细胞增多症对动物毛皮行业的发展构成威胁。针对AMDV的中和抗体可能导致持续感染，而不是为水貂提供保护。迄今为止，尚未开发出预防或治愈这种疾病的具体方法。为了消除水貂浆细胞增多症，抗体检测技术已在全球范围内作为筛选AMDV阳性水貂的主要方法。本文介绍了AMDV抗体检测方面的经典技术——对流免疫电泳和新兴技术，并对这些技术的未来发展进行了展望。
