Shah P K, Narendran V, Kalpana N
Department of Paediatric Retina and Ocular Oncology, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Coimbatore, India.
Eye (Lond). 2015 Aug;29(8):1046-50. doi: 10.1038/eye.2015.78. Epub 2015 May 22.
To report the safety and efficacy of simultaneous bilateral 25-gauge lens-sparing vitrectomy for vascularly active stage 4 retinopathy of prematurity (ROP).
Retrospective, noncomparative, consecutive case series. Twenty eyes of 10 babies who presented with vascularly active stage 4 ROP in both the eyes underwent simultaneous bilateral 25-gauge lens-sparing vitrectomy. After completing surgery for one eye, the other eye was re-prepped as performed before starting any new case of a different patient and an entire new set of disposable 25-gauge instruments were used. During the post-operative period parents were advised to keep separate eye drops for each eye and to wash their hands in between switching the eyes to put the drops.
The mean follow-up was 8.7 months (range 4-17 months). None of the cases developed any signs of infection. The anatomic success rate for stage 4a was 100% (11/11 eyes) and for stage 4b was 8/9 eyes (89%).
These results show that simultaneous bilateral 25-gauge lens-sparing vitrectomy for stage 4 ROP is a safe and effective procedure with a good outcome provided both eyes of the baby are treated as eyes of two different patients.
报告双眼同时行25G保留晶状体玻璃体切除术治疗4期活动性早产儿视网膜病变（ROP）的安全性和有效性。
回顾性、非对照、连续病例系列研究。10例双眼均为4期活动性ROP的婴儿的20只眼接受了双眼同时25G保留晶状体玻璃体切除术。一只眼完成手术后，另一只眼重新准备，如同开始新患者的任何新病例之前那样进行准备，并使用全新的一套一次性25G器械。术后期间，建议家长为每只眼准备单独的眼药水，并在更换眼睛滴眼药水时洗手。
平均随访8.7个月（范围4 - 17个月）。所有病例均未出现任何感染迹象。4a期的解剖成功率为100%（11/11只眼），4b期为8/9只眼（89%）。
这些结果表明，对于4期ROP，双眼同时行25G保留晶状体玻璃体切除术是一种安全有效的手术，若将婴儿的双眼当作两个不同患者的眼睛来治疗，则预后良好。
