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肺动静脉畸形作为栓塞性中风的病因:病例报告及文献复习

Pulmonary arteriovenous malformation as a cause of embolic stroke: case report and review of the literature.

作者信息

Anticoli Sabrina, Pezzella Francesca Romana, Siniscalchi Antonio, Gallelli Luca, Bravi Maria Cristina

机构信息

Stroke Unit Emergency Department, S. Camillo-Forlanini Hospital, Rome, Italy.

Department of Neurology, Annunziata Hospital, Cosenza, Italy.

出版信息

Interv Neurol. 2015 Jan;3(1):27-30. doi: 10.1159/000368969.

DOI:10.1159/000368969
PMID:25999989
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4436524/
Abstract

BACKGROUND

Pulmonary arteriovenous malformation (PAVM) is an abnormal communication between pulmonary arteries and veins responsible for right-to-left shunting that could induce the development of embolic stroke.

SUMMARY

We describe an 82-year-old woman without history of respiratory or neurological diseases, who presented at our observation unit with acute onset of cerebral ischemia. Clinical, laboratory and radiological findings diagnosed a PAVM.

KEY MESSAGES

Usually, endovascular procedures based on embolization or, alternatively, surgery represent the recommended treatment. However, both hormonal therapy and thrombolytic therapy can be used. In our patient, treatment with warfarin induced a remission of symptoms. This strategy should be tested in larger studies.

摘要

背景

肺动静脉畸形(PAVM)是肺动脉与静脉之间的异常分流,可导致右向左分流,进而引发栓塞性中风。

总结

我们描述了一名82岁女性,无呼吸或神经疾病史,因急性脑缺血入住我们的观察病房。临床、实验室和影像学检查结果诊断为PAVM。

关键信息

通常,基于栓塞的血管内手术或手术是推荐的治疗方法。然而,激素治疗和溶栓治疗也可使用。在我们的患者中,华法林治疗使症状缓解。这一策略应在更大规模的研究中进行验证。

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Amplatzer vascular plug IV for occlusion of pulmonary arteriovenous malformations in a patient with cryptogenic stroke.用于封堵不明原因卒中患者肺动静脉畸形的Amplatzer血管塞IV型
Ann Pediatr Cardiol. 2014 May;7(2):145-7. doi: 10.4103/0974-2069.132498.
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Transcatheter closure of a pulmonary arteriovenous malformation in a patient with hereditary hemorrhagic telangiectasia.遗传性出血性毛细血管扩张症患者经导管封堵肺动静脉畸形
Cardiovasc Interv Ther. 2015 Jul;30(3):270-2. doi: 10.1007/s12928-014-0276-2. Epub 2014 Jun 14.
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Large pulmonary arteriovenous malformations: long-term results of embolization with AMPLATZER vascular plugs.大型肺动静脉畸形:使用AMPLATZER血管封堵器栓塞的长期结果
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Catheter approach to redirect hepatic venous return for treatment of unilateral pulmonary arteriovenous malformations after fontan.经导管途径重定向肝静脉回流以治疗Fontan术后单侧肺动静脉畸形
Catheter Cardiovasc Interv. 2014 Jul 1;84(1):86-93. doi: 10.1002/ccd.25326. Epub 2014 Jan 7.
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[Surgical and endovascular treatment of lung arteriovenous malformations].肺动静脉畸形的手术及血管内治疗
Khirurgiia (Mosk). 2013(10):4-11.
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Pulmonary arteriovenous malformations.肺动静脉畸形。
Chest. 2013 Sep;144(3):1033-1044. doi: 10.1378/chest.12-0924.
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Successful percutaneous endovascular retrieval of a coil in the left ventricle which migrated during embolization for pulmonary arteriovenous malformation.成功经皮血管内取出在肺动静脉畸形栓塞过程中移位至左心室的弹簧圈。
Int J Cardiol. 2013 Feb 20;163(2):e33-5. doi: 10.1016/j.ijcard.2012.08.045. Epub 2012 Oct 4.
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Neurologist. 2012 Jan;18(1):44-8. doi: 10.1097/NRL.0b013e31823d7af0.
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