Yeung Jacky T, Matouk Charles C, Bulsara Ketan R, Sheth Kevin N
Department of Neurosurgery, Yale School of Medicine, New Haven, Conn., USA.
Department of Neurology, Yale School of Medicine, New Haven, Conn., USA.
Interv Neurol. 2015 Jan;3(1):31-40. doi: 10.1159/000368968.
Basilar artery occlusion is one of the most devastating neurological conditions known to man. Though rare, patients with clinical syndromes localized to this anatomical region are often referred to acute stroke and endovascular units. Recent studies evaluating the efficacy of endovascular approaches to stroke have focused on anterior circulation syndromes. In this review, we examine the approaches to stroke syndromes due to basilar artery thrombosis. We share the relevant data for intravenous and intra-arterial tissue plasminogen activator as well as mechanical approaches to restoring perfusion in this critical area of the brain.
基底动脉闭塞是人类已知的最具毁灭性的神经系统疾病之一。尽管罕见,但临床表现局限于该解剖区域的患者常被转诊至急性卒中及血管内治疗单元。近期评估血管内治疗卒中疗效的研究主要集中在前循环综合征。在本综述中,我们探讨了基底动脉血栓形成所致卒中综合征的治疗方法。我们分享了静脉及动脉内组织型纤溶酶原激活剂的相关数据,以及在这一关键脑区恢复灌注的机械治疗方法。