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美国成年人群中的小肠扭转:一项基于人群研究的结果。

Small bowel volvulus in the adult populace of the United States: results from a population-based study.

作者信息

Coe Taylor M, Chang David C, Sicklick Jason K

机构信息

Department of Surgery, University of California San Diego, UC San Diego Health System, San Diego, CA, USA.

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

出版信息

Am J Surg. 2015 Aug;210(2):201-210.e2. doi: 10.1016/j.amjsurg.2014.12.048. Epub 2015 Apr 30.

Abstract

BACKGROUND

Small bowel volvulus is a rare entity in Western adults. Greater insight into epidemiology and outcomes may be gained from a national database inquiry.

METHODS

The Nationwide Inpatient Sample (1998 to 2010), a 20% stratified sample of United States hospitals, was retrospectively reviewed for small bowel volvulus cases (International Classification of Diseases, 9th Edition [ICD-9] code 560.2 excluding gastric/colonic procedures) in patients greater than or equal to 18 years old.

RESULTS

There were 2,065,599 hospitalizations for bowel obstruction (ICD-9 560.x). Of those, there were 20,680 (1.00%) small bowel volvulus cases; 169 were attributable to intestinal malrotation. Most cases presented emergently (89.24%) and operative management was employed more frequently than nonoperative (65.21% vs 34.79%, P < .0001). Predictors of mortality included age greater than 50 years, Charlson comorbidity index greater than or equal to 1, emergent admission, peritonitis, acute vascular insufficiency, coagulopathy, and nonoperative management (P < .0001).

CONCLUSION

As the first population-based epidemiological study of small bowel volvulus, our findings provide a robust representation of this rare cause of small bowel obstruction in American adults.

摘要

背景

小肠扭转在西方成年人中是一种罕见疾病。通过全国性数据库查询可能会更深入地了解其流行病学和治疗结果。

方法

对全国住院患者样本(1998年至2010年)进行回顾性研究,该样本为美国医院20%的分层样本,纳入年龄大于或等于18岁的小肠扭转患者(国际疾病分类第九版[ICD-9]编码560.2,不包括胃/结肠手术)。

结果

因肠梗阻(ICD-9 560.x)住院的患者有2,065,599例。其中,小肠扭转病例有20,680例(1.00%);169例归因于肠旋转不良。大多数病例为急诊(89.24%),手术治疗的应用比非手术治疗更频繁(65.21%对34.79%,P <.0001)。死亡的预测因素包括年龄大于50岁、查尔森合并症指数大于或等于1、急诊入院、腹膜炎、急性血管功能不全、凝血障碍和非手术治疗(P <.0001)。

结论

作为第一项基于人群的小肠扭转流行病学研究,我们的研究结果有力地呈现了美国成年人中这种罕见的小肠梗阻病因。

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